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Baseline Body Composition in Prepubertal Short Stature Children with Severe and Moderate Growth Hormone Deficiency
المؤلفون المشاركون
Matusik, Pawel
Malecka-Tendera, Ewa
Klesiewicz, Marta
Klos, Karolina
Stasiulewicz, Martyna
Barylak, Aleksandra
Nazarkiewicz, Patrycja
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To compare body composition parameters in short children with severe versus moderate and no growth hormone deficiency (GHD).
Design and Method.
61 children (40 boys) were studied.
Height SDS, BMI Z-score, waist/height ratio (W/HtR), and body composition parameters (BIA) as fat tissue (FAT%), fat-free mass (FFM%), predicted muscle mass (PMM%), and total body water (TBW%) were evaluated.
GH secretion in the overnight profile and two stimulation tests and insulin-like growth factor 1 (IGF-1) level were measured.
Results.
Overall, in 16 (26%) moderate (7.0 > peak GH < 10 ng/mL) and in 11 (18%) severe (GH ≤ 7.0 ng/mL) GHD was diagnosed.
In children with sGHD BMI Z-score, W/HtR and FAT% were significantly higher, while FFM%, PMM%, and TBW% were significantly lower versus mGHD and versus noGHD subgroups.
No significant differences between mGHD and noGHD were found.
There were no differences in height SDS and IGF-1 SDS between evaluated subgroups.
Night GH peak level correlated significantly with FAT%, FFM%, PMM%, and TBW%, (p<0.05) in the entire group.
Conclusions.
Only sGHD is associated with significant impairment of body composition.
Body composition analysis may be a useful tool in distinguishing between its severe and moderate form of GHD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matusik, Pawel& Klesiewicz, Marta& Klos, Karolina& Stasiulewicz, Martyna& Barylak, Aleksandra& Nazarkiewicz, Patrycja…[et al.]. 2016. Baseline Body Composition in Prepubertal Short Stature Children with Severe and Moderate Growth Hormone Deficiency. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1105885
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matusik, Pawel…[et al.]. Baseline Body Composition in Prepubertal Short Stature Children with Severe and Moderate Growth Hormone Deficiency. International Journal of Endocrinology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1105885
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matusik, Pawel& Klesiewicz, Marta& Klos, Karolina& Stasiulewicz, Martyna& Barylak, Aleksandra& Nazarkiewicz, Patrycja…[et al.]. Baseline Body Composition in Prepubertal Short Stature Children with Severe and Moderate Growth Hormone Deficiency. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1105885
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1105885
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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