Pituitary Morphology and Function in 43 Children with Central Diabetes Insipidus
المؤلفون المشاركون
Liu, Wendong
Wang, Limin
Liu, Minghua
Li, Guimei
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
In pediatric central diabetes insipidus (CDI), etiology diagnosis and pituitary function monitoring are usually delayed.
This study aimed to illustrate the importance of regular follow-up and pituitary function monitoring in pediatric CDI.
Methods.
The clinical, hormonal, and neuroradiological characteristics of children with CDI at diagnosis and during 1.5–2-year follow-up were collected and analyzed.
Results.
The study included 43 CDI patients.
The mean interval between initial manifestation and diagnosis was 22.29 ± 3.67 months (range: 2–108 months).
The most common complaint was polyuria/polydipsia.
Causes included Langerhans cell histiocytosis, germinoma, and craniopharyngioma in 2, 5, and 4 patients; the remaining were idiopathic.
No significant changes were found during the 1.5–2 years after CDI diagnosis.
Twenty-three of the 43 cases (53.5%) had ≥1 anterior pituitary hormone deficiency.
Isolated growth hormone deficiency was the most frequent abnormality (37.5%) and was not associated with pituitary stalk diameter.
Multiple pituitary hormone deficiencies were found in 8 cases with pituitary stalk diameter > 4.5 mm.
Conclusion.
Diagnosis of CDI is usually delayed.
CDI with a pituitary stalk diameter > 4.5 mm carries a higher risk of multiple pituitary hormone deficiencies.
Long-term MRI and pituitary function follow-ups are necessary for children with idiopathic CDI.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Wendong& Wang, Limin& Liu, Minghua& Li, Guimei. 2016. Pituitary Morphology and Function in 43 Children with Central Diabetes Insipidus. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1105948
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Wendong…[et al.]. Pituitary Morphology and Function in 43 Children with Central Diabetes Insipidus. International Journal of Endocrinology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1105948
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Wendong& Wang, Limin& Liu, Minghua& Li, Guimei. Pituitary Morphology and Function in 43 Children with Central Diabetes Insipidus. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1105948
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1105948
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر