Putative Key Role of Inositol Messengers in Endothelial Cells in Preeclampsia

المؤلفون المشاركون

Scioscia, Marco
Kunjara, Sirilaksana
McLean, Patricia
Rademacher, Laurens
Rademacher, Thomas W.
Fascilla, Fabiana
Bettocchi, Stefano

المصدر

International Journal of Endocrinology

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-09-21

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الأحياء

الملخص EN

Immunological alterations, endothelial dysfunction, and insulin resistance characterize preeclampsia.

Endothelial cells hold the key role in the pathogenesis of this disease.

The signaling pathways mediating these biological abnormalities converge on PKB/Akt, an intracellular kinase regulating cell survival, proliferation, and metabolism.

Inositol second messengers are involved in metabolic and cell signaling pathways and are highly expressed during preeclampsia.

Intracellular action of these molecules is deeply affected by zinc, manganese, and calcium.

To evaluate the pathophysiological significance, we present the response of the intracellular pathways of inositol phosphoglycans involved in cellular metabolism and propose a link with the disease.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kunjara, Sirilaksana& McLean, Patricia& Rademacher, Laurens& Rademacher, Thomas W.& Fascilla, Fabiana& Bettocchi, Stefano…[et al.]. 2016. Putative Key Role of Inositol Messengers in Endothelial Cells in Preeclampsia. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1105981

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kunjara, Sirilaksana…[et al.]. Putative Key Role of Inositol Messengers in Endothelial Cells in Preeclampsia. International Journal of Endocrinology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1105981

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kunjara, Sirilaksana& McLean, Patricia& Rademacher, Laurens& Rademacher, Thomas W.& Fascilla, Fabiana& Bettocchi, Stefano…[et al.]. Putative Key Role of Inositol Messengers in Endothelial Cells in Preeclampsia. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1105981

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1105981