The Relationship between Adiposity and Insulin Sensitivity in African Women Living with the Polycystic Ovarian Syndrome: A Clamp Study
المؤلفون المشاركون
Doh, Emmanuella
Mbanya, Armand
Dohbit, Sama
Tchana-Sinou, Mycilline
Foumane, Pascal
Donfack, Olivier Trésor
Mbanya, Jean Claude
Sobngwi, Eugene
Kemfang Ngowa, J. D.
Doh, A. S.
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
We aimed to assess the variation of insulin sensitivity in relation to obesity in women living with PCOS in a sub-Sahara African setting.
Methods.
We studied body composition, insulin sensitivity, and resting energy expenditure in 14 PCOS patients (6 obese and 8 nonobese) compared to 10 matched nonobese non-PCOS subjects.
Insulin sensitivity was assessed using the gold standard 80 mU/m2/min euglycemic-hyperinsulinemic clamp and resting energy expenditure was measured by indirect calorimetry.
Results.
Insulin sensitivity adjusted to lean mass was lowest in obese PCOS subjects and highest in healthy subjects (11.2 [ 10.1–12.4 ] versus 12.9 [ 12.1–13.8 ] versus 16.6 [ 13.8–17.9 ] , p = 0.012 ); there was a tendency for resting energy expenditure adjusted for total body mass to decrease across the groups highest in obese PCOS subjects (1411 [ 1368–1613 ] versus 1274 [ 1174–1355 ] versus 1239 [ 1195–1454 ] , p = 0.306 ).
Conclusion.
In this sub-Saharan population, insulin resistance is associated with PCOS per se but is further aggravated by obesity.
Obesity did not seem to be explained by low resting energy expenditure suggesting that dietary intake may be a determinant of the obesity in this context.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Doh, Emmanuella& Mbanya, Armand& Kemfang Ngowa, J. D.& Dohbit, Sama& Tchana-Sinou, Mycilline& Foumane, Pascal…[et al.]. 2016. The Relationship between Adiposity and Insulin Sensitivity in African Women Living with the Polycystic Ovarian Syndrome: A Clamp Study. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106047
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Doh, Emmanuella…[et al.]. The Relationship between Adiposity and Insulin Sensitivity in African Women Living with the Polycystic Ovarian Syndrome: A Clamp Study. International Journal of Endocrinology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1106047
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Doh, Emmanuella& Mbanya, Armand& Kemfang Ngowa, J. D.& Dohbit, Sama& Tchana-Sinou, Mycilline& Foumane, Pascal…[et al.]. The Relationship between Adiposity and Insulin Sensitivity in African Women Living with the Polycystic Ovarian Syndrome: A Clamp Study. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106047
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106047
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر