Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer
المؤلفون المشاركون
Chao, Tzu-Chieh
Tsang, Ngan-Ming
Liou, Miaw-Jene
Hsueh, Chuen
Lin, Jen-Der
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The aims of this study were to analyze the clinical characteristics of SPM in patients with well-differentiated thyroid cancer and to determine the long-term prognosis in patients with double malignancies.
Materials and Methods.
We retrospectively analyzed 2,864 patients with well-differentiated thyroid cancer and a mean age of 44.0±14.4 years.
Of these, 200 (7.0%) were diagnosed with SPM, 115 of which were diagnosed with metachronous SPM.
Results.
Of 2,864 patients, 163 (5.7%) patients died of thyroid cancer and 301 (10.5%) died of any cause by the end of the follow-up period.
Multivariate analysis identified age, SPM, external radiotherapy, TNM stage, and postoperative serum Tg level to be factors independently associated with decreased survival.
Of 200 patients with SPM, 74 (37.0%) died.
In comparison to the anachronous and synchronous groups, the metachronous SPM group had a higher mean age; more advanced tumor, node, and metastasis stage; lower remission rate; higher postoperative radioactive iodide (131I) accumulated dose; a higher proportion of patients who underwent external radiotherapy; and higher thyroid cancer and total mortality rates.
Conclusions.
Patients with well-differentiated thyroid carcinoma and metachronous SPM had worse prognoses compared to patients without SPM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liou, Miaw-Jene& Tsang, Ngan-Ming& Hsueh, Chuen& Chao, Tzu-Chieh& Lin, Jen-Der. 2016. Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106054
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liou, Miaw-Jene…[et al.]. Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer. International Journal of Endocrinology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1106054
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liou, Miaw-Jene& Tsang, Ngan-Ming& Hsueh, Chuen& Chao, Tzu-Chieh& Lin, Jen-Der. Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106054
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106054
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر