Different Nodules Identified during Liver Explant Gross Examination: Relevance and Need for Sectioning—Experience from India
المؤلفون المشاركون
Bansal, Nalini
Vij, Vivek
Rastogi, Mukul
المصدر
International Journal of Hepatology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-22
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
The goal of this study was to determine the etiopathological association of various hepatic nodules identified during gross examination of liver explants specimen and the grossing aspects of these abnormal nodules especially those smaller than 1 cm in diameter.
Our aim was to analyze whether there is any association of macroregenerative and dysplastic nodule with hepatocellular carcinoma.
Materials and Methods.
Fifty consecutive liver explants specimens were analyzed for the presence of any abnormal nodule (abnormal nodule defined as any nodule different in color, texture, and appearance from adjacent liver tissue).
Results.
Of the total 40 abnormal nodules identified in 50 liver explant specimens, there were 12 (30%) HCC [including 5 small HCC (41% of total HCC) and 1 steatohepatitic HCC (8% of total HCC)], 11 (27%) MRNs, 8 (20%) dysplastic nodules, and 9 (22%) necrotic nodules.
Most cases (72%) of MRN are seen in hepatitis C virus related cirrhosis with only 2 cases having associated HCC.
Most cases of HCC were seen in cases of HBV associated cirrhosis (60%).
The association of MRN was not found to be significantly associated with HCC with a p value of 1.0.
Dysplastic nodules were found to be significantly associated with HCC with a p value of 0.02.
Conclusion.
In hepatic carcinogenesis, the role of MRN does not appear to be significant.
However, the presence of dysplastic nodules is significantly associated with HCC.
The study identified another variant of cirrhotic nodules herein called necrotic nodules that are mostly tan greenish in color and <0.5 cm in diameter.
No dysplastic changes were identified in any of these nodules disqualifying the need of sectioning in such nodules.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bansal, Nalini& Vij, Vivek& Rastogi, Mukul. 2016. Different Nodules Identified during Liver Explant Gross Examination: Relevance and Need for Sectioning—Experience from India. International Journal of Hepatology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106215
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bansal, Nalini…[et al.]. Different Nodules Identified during Liver Explant Gross Examination: Relevance and Need for Sectioning—Experience from India. International Journal of Hepatology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1106215
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bansal, Nalini& Vij, Vivek& Rastogi, Mukul. Different Nodules Identified during Liver Explant Gross Examination: Relevance and Need for Sectioning—Experience from India. International Journal of Hepatology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106215
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106215
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر