Comparison of Procleix Ultrio Elite and Procleix Ultrio NAT Assays for Screening of Transfusion Transmitted Infections among Blood Donors in India
المؤلفون المشاركون
Zaman, Shamsuz
Chaurasia, Rahul
Chatterjee, Kabita
Rout, Diptiranjan
Pandey, Hem Chandra
Maurya, Abhishek Kumar
المصدر
International Journal of Microbiology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Introduction of nucleic acid testing (NAT) has helped in decreasing window period donations, resulting in increased safety of blood supplies.
NAT combines the advantages of direct and highly sequence-specific detection of viral genomes.
We analysed the performance of newer Procleix Ultrio Elite (PUE) and Procleix Ultrio assay (PUA) for the screening of the viral markers in our donor population.
Material and Methods.
10,015 donor samples were screened by routine immunoassays and both versions of NAT.
NAT yields detected were subjected to viral load estimation and to other serological markers.
Results.
A total of 21 NAT yields were detected; three were positive by both NAT systems, whereas 18 samples were reactive by PUE only.
NAT yields include 18 HBV and 3 HCV yields, of which 17 HBV yields were occult infections and 1 was window period (WP) infection.
All 3 HCV yields were WP infections.
No HIV-1/HIV-2 yield was found.
Conclusion.
Efficient target capture chemistry in the new TMA assay version significantly improved sensitivity.
NAT is superior to serological immunoassays for screening of the viral markers; and the efficient target capture system in the newer TMA assay, namely, the PUE system, has significantly improved sensitivity over the earlier versions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chaurasia, Rahul& Rout, Diptiranjan& Zaman, Shamsuz& Chatterjee, Kabita& Pandey, Hem Chandra& Maurya, Abhishek Kumar. 2016. Comparison of Procleix Ultrio Elite and Procleix Ultrio NAT Assays for Screening of Transfusion Transmitted Infections among Blood Donors in India. International Journal of Microbiology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106257
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chaurasia, Rahul…[et al.]. Comparison of Procleix Ultrio Elite and Procleix Ultrio NAT Assays for Screening of Transfusion Transmitted Infections among Blood Donors in India. International Journal of Microbiology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1106257
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chaurasia, Rahul& Rout, Diptiranjan& Zaman, Shamsuz& Chatterjee, Kabita& Pandey, Hem Chandra& Maurya, Abhishek Kumar. Comparison of Procleix Ultrio Elite and Procleix Ultrio NAT Assays for Screening of Transfusion Transmitted Infections among Blood Donors in India. International Journal of Microbiology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106257
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106257
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر