Susceptibility Profiles of Mycobacterium ulcerans Isolates to Streptomycin and Rifampicin in Two Districts of the Eastern Region of Ghana
المؤلفون المشاركون
Owusu, Enid
Newman, Mercy Jemima
Kotey, Nana Konama
Akumwena, Amos
Bannerman, Elizabeth
المصدر
International Journal of Microbiology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-14
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Drug resistance is a major challenge in antibiotic chemotherapy.
Assessing resistance profiles of pathogens constitutes an essential surveillance tool in the epidemiology and control of infectious diseases, including Buruli ulcer (BU) disease.
With the successful definitive management of BU using rifampicin and streptomycin, little attention had been paid to monitoring emergence of resistant Mycobacterium ulcerans (M.
ulcerans) isolates in endemic communities.
This study investigated the susceptibility profiles of M.
ulcerans isolates from two BU endemic areas in Ghana to streptomycin and rifampicin.
Methods.
The antibiotic susceptibility of seventy (70) M.
ulcerans isolates to rifampicin and streptomycin was determined simultaneously at critical concentrations of 40 µg/mL and 4 µg/mL, respectively, by the Canetti proportion method.
Results.
Resistance to rifampicin was observed for 12 (17.1%) M.
ulcerans isolates tested, whilst 2 (2.9%) showed resistance to streptomycin.
None of the isolates tested showed dual resistance to both rifampicin and streptomycin.
Conclusion.
Outcomes from this study may not be reflective of all BU endemic communities; it, however, provides information on the resistance status of the isolates, which is useful for monitoring of M.
ulcerans, as well as BU disease surveillance and control.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Owusu, Enid& Newman, Mercy Jemima& Kotey, Nana Konama& Akumwena, Amos& Bannerman, Elizabeth. 2016. Susceptibility Profiles of Mycobacterium ulcerans Isolates to Streptomycin and Rifampicin in Two Districts of the Eastern Region of Ghana. International Journal of Microbiology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106286
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Owusu, Enid…[et al.]. Susceptibility Profiles of Mycobacterium ulcerans Isolates to Streptomycin and Rifampicin in Two Districts of the Eastern Region of Ghana. International Journal of Microbiology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1106286
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Owusu, Enid& Newman, Mercy Jemima& Kotey, Nana Konama& Akumwena, Amos& Bannerman, Elizabeth. Susceptibility Profiles of Mycobacterium ulcerans Isolates to Streptomycin and Rifampicin in Two Districts of the Eastern Region of Ghana. International Journal of Microbiology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1106286
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106286
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر