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Serum Endocan Levels Associated with Hypertension and Loss of Renal Function in Pediatric Patients after Two Years from Renal Transplant
المؤلفون المشاركون
Oliveira, Vanessa
Souza, Livia Victorino de
Laurindo, Aline Oliveira
Huarachı, DelmaRegına Gomes
Nogueira, Paulo Cesar Koch
Feltran, Luciana de Santis
Medina-Pestana, José Osmar
Franco, Maria do Carmo
المصدر
International Journal of Nephrology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Endocan is an important biomarker of inflammation and endothelial dysfunction that increases in association with several chronic diseases.
Few published data have described the role of endocan in pediatric renal transplant (RT) patients.
We evaluated the endocan concentrations in 62 children who underwent renal transplantation and assessed their relationships with the patients’ blood pressure and loss of renal function.
The endocan levels were significantly elevated in the pediatric RT patients who had hypertension and a loss of renal function.
We determined positive correlations between the endocan concentrations and the hemodynamic variables (systolic blood pressure: r=0.416; P=0.001; pulse pressure: r=0.412; P=0.003).
The endocan levels were inversely correlated with the estimated glomerular filtration rate (r=-0.388; P=0.003).
An endocan cutoff concentration of 7.0 ng/mL identified pediatric RT patients who had hypertension and a loss of renal function with 100% sensitivity and 75% specificity.
In conclusion, the endocan concentrations were significantly elevated in pediatric RT patients who had both hypertension and a loss of renal function.
The correlations between the endocan levels and the hemodynamic variables and the markers of renal function strengthen the hypothesis that it is an important marker of cardiorenal risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Souza, Livia Victorino de& Oliveira, Vanessa& Laurindo, Aline Oliveira& Huarachı, DelmaRegına Gomes& Nogueira, Paulo Cesar Koch& Feltran, Luciana de Santis…[et al.]. 2016. Serum Endocan Levels Associated with Hypertension and Loss of Renal Function in Pediatric Patients after Two Years from Renal Transplant. International Journal of Nephrology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106339
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Souza, Livia Victorino de…[et al.]. Serum Endocan Levels Associated with Hypertension and Loss of Renal Function in Pediatric Patients after Two Years from Renal Transplant. International Journal of Nephrology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1106339
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Souza, Livia Victorino de& Oliveira, Vanessa& Laurindo, Aline Oliveira& Huarachı, DelmaRegına Gomes& Nogueira, Paulo Cesar Koch& Feltran, Luciana de Santis…[et al.]. Serum Endocan Levels Associated with Hypertension and Loss of Renal Function in Pediatric Patients after Two Years from Renal Transplant. International Journal of Nephrology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106339
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106339
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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