Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy

المؤلفون المشاركون

Compton, Gregory
Nield, Lynne
Dragulescu, Andreea
Benson, Lee
Grosse-Wortmann, Lars

المصدر

International Journal of Pediatrics

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-11-15

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الملخص EN

Introduction.

Hypertrophic cardiomyopathy (HCM) is burdened with morbidity and mortality including tachyarrhythmias and sudden cardiac death.

These complications are attributed in part to the formation of proarrhythmic scars in the myocardium.

The presence of extensive LGE is a risk factor for adverse outcomes in HCM.

Late gadolinium enhancement (LGE) cardiac magnetic resonance imaging (cMRI) is the standard for the noninvasive evaluation of myocardial scars.

However, echocardiography represents an attractive screening tool for myocardial scarring.

The aim of this study was to compare the suitability of echocardiography to detect myocardial scars to the standard of cMRI-LGE.

Methods.

The cMRI studies and echocardiograms from 56 consecutive children with HCM were independently evaluated for the presence of cMRI-LGE and echocardiographic evidence of scarring by expert readers.

Results.

Echocardiography had a high sensitivity (93%) and negative predictive value (94%) in comparison to LGE.

The false positive rate was high, leading to a low specificity (37%) and a low positive predictive value (35%).

Conclusions.

Given the poor specificity and positive predictive value, echocardiography is not a suitable screening test for the presence of myocardial scarring in children with HCM.

However, children without echocardiographic evidence of myocardial scarring may not need to undergo cardiac magnetic resonance imaging to “rule in” LGE.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Compton, Gregory& Nield, Lynne& Dragulescu, Andreea& Benson, Lee& Grosse-Wortmann, Lars. 2016. Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy. International Journal of Pediatrics،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106568

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Compton, Gregory…[et al.]. Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy. International Journal of Pediatrics No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1106568

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Compton, Gregory& Nield, Lynne& Dragulescu, Andreea& Benson, Lee& Grosse-Wortmann, Lars. Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy. International Journal of Pediatrics. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106568

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1106568