Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy
Joint Authors
Compton, Gregory
Nield, Lynne
Dragulescu, Andreea
Benson, Lee
Grosse-Wortmann, Lars
Source
International Journal of Pediatrics
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Hypertrophic cardiomyopathy (HCM) is burdened with morbidity and mortality including tachyarrhythmias and sudden cardiac death.
These complications are attributed in part to the formation of proarrhythmic scars in the myocardium.
The presence of extensive LGE is a risk factor for adverse outcomes in HCM.
Late gadolinium enhancement (LGE) cardiac magnetic resonance imaging (cMRI) is the standard for the noninvasive evaluation of myocardial scars.
However, echocardiography represents an attractive screening tool for myocardial scarring.
The aim of this study was to compare the suitability of echocardiography to detect myocardial scars to the standard of cMRI-LGE.
Methods.
The cMRI studies and echocardiograms from 56 consecutive children with HCM were independently evaluated for the presence of cMRI-LGE and echocardiographic evidence of scarring by expert readers.
Results.
Echocardiography had a high sensitivity (93%) and negative predictive value (94%) in comparison to LGE.
The false positive rate was high, leading to a low specificity (37%) and a low positive predictive value (35%).
Conclusions.
Given the poor specificity and positive predictive value, echocardiography is not a suitable screening test for the presence of myocardial scarring in children with HCM.
However, children without echocardiographic evidence of myocardial scarring may not need to undergo cardiac magnetic resonance imaging to “rule in” LGE.
American Psychological Association (APA)
Compton, Gregory& Nield, Lynne& Dragulescu, Andreea& Benson, Lee& Grosse-Wortmann, Lars. 2016. Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy. International Journal of Pediatrics،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106568
Modern Language Association (MLA)
Compton, Gregory…[et al.]. Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy. International Journal of Pediatrics No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1106568
American Medical Association (AMA)
Compton, Gregory& Nield, Lynne& Dragulescu, Andreea& Benson, Lee& Grosse-Wortmann, Lars. Echocardiography as a Screening Test for Myocardial Scarring in Children with Hypertrophic Cardiomyopathy. International Journal of Pediatrics. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106568
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1106568