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Potential of IL-33 for Preventing the Kidney Injury via Regulating the Lipid Metabolism in Gout Patients
المؤلفون المشاركون
Duan, Lihua
Shi, Guixiu
He, Yan
Qian, Hongyan
Huang, Yan
Su, Qun
Lin, Qingyan
Liu, Wen
Luo, Jiao
Yu, Bing
Liu, Yuan
Chen, Jie
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-07
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Interleukin-33 (IL-33), the most recently discovered member of the IL-1 superfamily, has been linked to several human pathologies including autoimmune diseases, sepsis, and allergy through its specific IL-1 receptor ST2.
However, there is little information regarding the role of IL-33 in gout.
In this study, we investigated the potential role of IL-33 in gout patients.
The serum level of IL-33 was measured by ELISA, and the clinical and laboratory parameters, serum creatinine, urea, and lipid, were extracted from medical record system.
The serum IL-33 expression was predominantly increased in gout patients compared to healthy controls, and the IL-33 levels were higher in patients without kidney injury.
Furthermore, IL-33 showed a negative correlation with biomarkers of kidney injury, such as CRE and urea.
The lipid metabolism dysfunction, tophi, and hypertension are the common reasons for kidney injury in gout.
Interestingly, inverse and positive correlation of IL-33 expression was observed in LDL and HDL, respectively.
However, there was no significant alteration in the gout patients with hypertension and tophi.
These data suggested that IL-33 might act as a protective role in kidney injury through regulating the lipid metabolism in gout.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Duan, Lihua& Huang, Yan& Su, Qun& Lin, Qingyan& Liu, Wen& Luo, Jiao…[et al.]. 2016. Potential of IL-33 for Preventing the Kidney Injury via Regulating the Lipid Metabolism in Gout Patients. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107944
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Duan, Lihua…[et al.]. Potential of IL-33 for Preventing the Kidney Injury via Regulating the Lipid Metabolism in Gout Patients. Journal of Diabetes Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1107944
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Duan, Lihua& Huang, Yan& Su, Qun& Lin, Qingyan& Liu, Wen& Luo, Jiao…[et al.]. Potential of IL-33 for Preventing the Kidney Injury via Regulating the Lipid Metabolism in Gout Patients. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107944
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1107944
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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