GDF-15 and Hepcidin Levels in Nonanemic Patients with Impaired Glucose Tolerance
المؤلفون المشاركون
Gülbahar, Özlem
Altınova, Eroğlu
Aktürk, Müjde
Törüner, Baloş
Yalcin, Mehmet Muhittin
Arslan, Emre
Ors Sendogan, Damla
Yetkin, Ilhan
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-25
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aims.
Growth Differentiation Factor-15 (GDF-15) has been suggested as one of the regulators of hepcidin, an important regulatory peptide for iron deposition.
Current data is conflicting about the relationship between hepcidin and disorders of glucose metabolism.
We aimed to investigate serum hepcidin and GDF-15 concentrations and their associations with each other, in nonanemic subjects with impaired glucose tolerance (IGT) in comparison with the nonanemic subjects with normal glucose tolerance (NGT).
Methods.
Thirty-seven subjects with IGT and 32 control subjects with NGT, who were age-, gender-, and body mass index- (BMI-) matched, were included in the study.
Results.
Serum GDF-15 levels were significantly higher in IGT compared to NGT.
There were no differences in hepcidin, interleukin-6, and high sensitive C-reactive protein levels between the groups.
We found a positive correlation between GDF-15 and hepcidin levels.
There were also positive correlations between GDF-15 and age, uric acid, creatinine, and area under the curve for glucose (AUC-G).
Hepcidin was correlated positively with ferritin levels.
In the multiple regression analysis, GDF-15 concentrations were independently associated with age, uric acid, and AUC-G.
Conclusions.
Impaired glucose tolerance is associated with increased GDF-15 levels even in the absence of anemia, but the levels of hepcidin are not significantly altered in prediabetic state.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yalcin, Mehmet Muhittin& Altınova, Eroğlu& Aktürk, Müjde& Gülbahar, Özlem& Arslan, Emre& Ors Sendogan, Damla…[et al.]. 2016. GDF-15 and Hepcidin Levels in Nonanemic Patients with Impaired Glucose Tolerance. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1107949
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yalcin, Mehmet Muhittin…[et al.]. GDF-15 and Hepcidin Levels in Nonanemic Patients with Impaired Glucose Tolerance. Journal of Diabetes Research No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1107949
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yalcin, Mehmet Muhittin& Altınova, Eroğlu& Aktürk, Müjde& Gülbahar, Özlem& Arslan, Emre& Ors Sendogan, Damla…[et al.]. GDF-15 and Hepcidin Levels in Nonanemic Patients with Impaired Glucose Tolerance. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1107949
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1107949
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر