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Urinary Biomarkers in the Assessment of Early Diabetic Nephropathy
المؤلفون المشاركون
Gluhovschi, Cristina
Gluhovschi, Gheorghe
Petrica, Ligia
Velciov, Silvia
Timar, Romulus
Ionita, Ioana
Kaycsa, Adriana
Timar, Bogdan
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-16
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Diabetic nephropathy (DN) is a frequent and severe complication of diabetes mellitus (DM).
Its diagnosis in incipient stages may allow prompt interventions and an improved prognosis.
Towards this aim, biomarkers for detecting early DN can be used.
Microalbuminuria has been proven a remarkably useful biomarker, being used for diagnosis of DN, for assessing its associated condition—mainly cardiovascular ones—and for monitoring its progression.
New researches are pointing that some of these biomarkers (i.e., glomerular, tubular, inflammation markers, and biomarkers of oxidative stress) precede albuminuria in some patients.
However, their usefulness is widely debated in the literature and has not yet led to the validation of a new “gold standard” biomarker for the early diagnosis of DN.
Currently, microalbuminuria is an important biomarker for both glomerular and tubular injury.
Other glomerular biomarkers (transferrin and ceruloplasmin) are under evaluation.
Tubular biomarkers in DN seem to be of a paramount importance in the early diagnosis of DN since tubular lesions occur early.
Additionally, biomarkers of inflammation, oxidative stress, podocyte biomarkers, and vascular biomarkers have been employed for assessing early DN.
The purpose of this review is to provide an overview of the current biomarkers used for the diagnosis of early DN.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gluhovschi, Cristina& Gluhovschi, Gheorghe& Petrica, Ligia& Timar, Romulus& Velciov, Silvia& Ionita, Ioana…[et al.]. 2016. Urinary Biomarkers in the Assessment of Early Diabetic Nephropathy. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1108124
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gluhovschi, Cristina…[et al.]. Urinary Biomarkers in the Assessment of Early Diabetic Nephropathy. Journal of Diabetes Research No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1108124
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gluhovschi, Cristina& Gluhovschi, Gheorghe& Petrica, Ligia& Timar, Romulus& Velciov, Silvia& Ionita, Ioana…[et al.]. Urinary Biomarkers in the Assessment of Early Diabetic Nephropathy. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1108124
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108124
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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