Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration
المؤلفون المشاركون
Chuang, Lee-Ming
Karnchanasorn, Rudruidee
Samoa, Raynald
Chiu, Ken C.
Huang, Jean
Ou, Horng-Yih
Feng, Wei
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-11
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
To determine the effectiveness of hemoglobin A1c (HbA1c) ≥ 6.5% in diagnosing diabetes compared to fasting plasma glucose (FPG) ≥ 126 mg/dL and 2-hour plasma glucose (2hPG) ≥ 200 mg/dL in a previously undiagnosed diabetic cohort, we included 5,764 adult subjects without established diabetes for whom HbA1c, FPG, 2hPG, and BMI measurements were collected.
Compared to the FPG criterion, the sensitivity of HbA1c ≥ 6.5% was only 43.3% (106 subjects).
Compared to the 2hPG criterion, the sensitivity of HbA1c ≥ 6.5% was only 28.1% (110 subjects).
Patients who were diabetic using 2hPG criterion but had HbA1c < 6.5% were more likely to be older ( 64 ± 15 versus 60 ± 15 years old, P = 0.01 , mean ± STD), female (53.2% versus 38.2%, P = 0.008 ), leaner ( 29.7 ± 6.1 versus 33.0 ± 6.6 kg/m2, P = 0.00000 5 ), and less likely to be current smokers (18.1% versus 29.1%, P = 0.02 ) as compared to those with HbA1c ≥ 6.5%.
The diagnostic agreement in the clinical setting revealed the current HbA1c ≥ 6.5% is less likely to detect diabetes than those defined by FPG and 2hPG.
HbA1c ≥ 6.5% detects less than 50% of diabetic patients defined by FPG and less than 30% of diabetic patients defined by 2hPG.
When the diagnosis of diabetes is in doubt by HbA1c, FPG and/or 2hPG should be obtained.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Karnchanasorn, Rudruidee& Huang, Jean& Ou, Horng-Yih& Feng, Wei& Chuang, Lee-Ming& Chiu, Ken C.…[et al.]. 2016. Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108192
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Karnchanasorn, Rudruidee…[et al.]. Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration. Journal of Diabetes Research No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1108192
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Karnchanasorn, Rudruidee& Huang, Jean& Ou, Horng-Yih& Feng, Wei& Chuang, Lee-Ming& Chiu, Ken C.…[et al.]. Comparison of the Current Diagnostic Criterion of HbA1c with Fasting and 2-Hour Plasma Glucose Concentration. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108192
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108192
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر