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The Actions of Lyophilized Apple Peel on the Electrical Activity and Organization of the Ventricular Syncytium of the Hearts of Diabetic Rats
المؤلفون المشاركون
Martínez Martínez, Alejandro
Martínez-Ladrón de Guevara, Elideth
Pérez-Hernández, Nury
Villalobos-López, Miguel Ángel
Pérez-Ishiwara, David Guillermo
Hernández-García, Vicente
Salas-Benito, Juan Santiago
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-29
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
This study was designed to examine the effects of lyophilized red delicious apple peel (RDP) on the action potentials (APs) and the input resistance-threshold current relationship.
The experiments were performed on isolated papillary heart muscles from healthy male rats, healthy male rats treated with RDP, diabetic male rats, and diabetic male rats treated with RDP.
The preparation was superfused with oxygenated Tyrode’s solution at 37°C.
The stimulation and the recording of the APs, the input resistance, and the threshold current were made using conventional electrophysiological methods.
The RDP presented no significant effect in normal rats.
Equivalent doses in diabetic rats reduced the APD and ARP.
The relationship between input resistance and threshold current established an inverse correlation.
The results indicate the following: (1) The functional structure of the cardiac ventricular syncytium in healthy rats is heterogeneous, in terms of input resistance and threshold current.
Diabetes further accentuates the heterogeneity.
(2) As a consequence, conduction block occurs and increases the possibility of reentrant arrhythmias.
(3) These modifications in the ventricular syncytium, coupled with the increase in the ARP, are the adequate substrate so that, with diabetes, the heart becomes more arrhythmogenic.
(4) RDP decreases the APD, the ARP, and most syncytium irregularity caused by diabetes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Martínez-Ladrón de Guevara, Elideth& Pérez-Hernández, Nury& Villalobos-López, Miguel Ángel& Pérez-Ishiwara, David Guillermo& Salas-Benito, Juan Santiago& Martínez Martínez, Alejandro…[et al.]. 2015. The Actions of Lyophilized Apple Peel on the Electrical Activity and Organization of the Ventricular Syncytium of the Hearts of Diabetic Rats. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108269
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Martínez-Ladrón de Guevara, Elideth…[et al.]. The Actions of Lyophilized Apple Peel on the Electrical Activity and Organization of the Ventricular Syncytium of the Hearts of Diabetic Rats. Journal of Diabetes Research No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1108269
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Martínez-Ladrón de Guevara, Elideth& Pérez-Hernández, Nury& Villalobos-López, Miguel Ángel& Pérez-Ishiwara, David Guillermo& Salas-Benito, Juan Santiago& Martínez Martínez, Alejandro…[et al.]. The Actions of Lyophilized Apple Peel on the Electrical Activity and Organization of the Ventricular Syncytium of the Hearts of Diabetic Rats. Journal of Diabetes Research. 2015. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108269
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108269
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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