Assessment of Insulin Resistance in Subjects with Normal Glucose Tolerance, Hyperinsulinemia with Normal Blood Glucose Tolerance, Impaired Glucose Tolerance, and Newly Diagnosed Type 2 Diabetes (Prediabetes Insulin Resistance Research)
المؤلفون المشاركون
Yang, Guang
Li, Chunlin
Gong, Yanping
Fang, Fusheng
Tian, Hui
Li, Jian
Cheng, Xiaoling
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-07
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Aim.
To evaluate the differences in insulin resistance (IR) among subjects with normal glucose tolerance (NGT), hyperinsulinemia with NGT (HINS), impaired glucose tolerance (IGT), and newly diagnosed type 2 diabetes mellitus (T2DM).
Methods.
5 NGT, 25 HINS, 25 IGT, and 25 T2DM subjects participated in this research.
The hyperinsulinemic-euglycemic clamp technique (HECT) was performed in all of them to evaluate IR levels.
The relative factors influencing IR were evaluated.
The simple insulin sensitivity indices were calculated, and the correlation between each index and the M value was analyzed.
Results.
The M values of NGT, HINS, IGT, and T2DM groups were 11.88 ± 2.93 mg·kg−1·min−1, 6.23 ± 1.73 mg·kg−1·min−1, 6.37 ± 2.12 mg·kg−1·min−1, and 6.19 ± 1.89 mg·kg−1·min−1, respectively.
M values in HINS, IGT, and T2DM groups were lower than those in the NGT group (P=0.005); however, the differences among the HINS, IGT, and T2DM groups were not statistically significant (P=0.835).
The independent factors influencing the M value were waistline and fasting insulin level (FINS).
The simple insulin sensitivity indices, especially Matsuda and Gutt index, were significantly associated with the M value (P<0.01).
Conclusion.
IR existed in the HINS, IGT, and T2DM groups, and IR levels were consistent in the three groups.
The independent factors influencing IR were waistline and FINS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Guang& Li, Chunlin& Gong, Yanping& Fang, Fusheng& Tian, Hui& Li, Jian…[et al.]. 2015. Assessment of Insulin Resistance in Subjects with Normal Glucose Tolerance, Hyperinsulinemia with Normal Blood Glucose Tolerance, Impaired Glucose Tolerance, and Newly Diagnosed Type 2 Diabetes (Prediabetes Insulin Resistance Research). Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108323
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Guang…[et al.]. Assessment of Insulin Resistance in Subjects with Normal Glucose Tolerance, Hyperinsulinemia with Normal Blood Glucose Tolerance, Impaired Glucose Tolerance, and Newly Diagnosed Type 2 Diabetes (Prediabetes Insulin Resistance Research). Journal of Diabetes Research No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1108323
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Guang& Li, Chunlin& Gong, Yanping& Fang, Fusheng& Tian, Hui& Li, Jian…[et al.]. Assessment of Insulin Resistance in Subjects with Normal Glucose Tolerance, Hyperinsulinemia with Normal Blood Glucose Tolerance, Impaired Glucose Tolerance, and Newly Diagnosed Type 2 Diabetes (Prediabetes Insulin Resistance Research). Journal of Diabetes Research. 2015. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108323
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108323
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر