The LINA Study: Higher Sensitivity of Infant Compared to Maternal EosinophilBasophil Progenitors to Indoor Chemical Exposures
المؤلفون المشاركون
Simon, Jan C.
Lehmann, Irina
Herberth, Gunda
Hörnig, Friederike
Kohajda, Tibor
Röder, Stefan
Borte, Michael
Diez, Ulrike
Rolle-Kampczyk, Ulrike
Denburg, Judah A.
Junge, Kristin M.
von Bergen, Martin
المصدر
Journal of Environmental and Public Health
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-26
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Purpose.
Enhanced eosinophil/basophil (Eo/B) progenitor cell levels are known to be associated with allergic inflammation and atopy risk.
The aim of the present study was to investigate the influence of different indoor exposures on the recruitment and differentiation of Eo/B progenitors in mother-child pairs.
Methods.
In 68 mother-child pairs of the LINA study peripheral blood mononuclear cells were used to assess Eo/B colony forming units (CFUs).
Information about disease outcomes and indoor exposures was obtained from questionnaires.
Indoor concentrations of volatile organic compounds (VOCs) were measured by passive sampling.
Results.
Infant’s Eo/B CFUs were positively associated with exposure to tobacco smoke, disinfectants, or VOCs.
In contrast, for maternal Eo/B CFUs, only a few associations were seen.
Higher numbers of infant Eo/B CFUs were observed in children with wheezing symptoms within the second year of life.
Conclusions.
We demonstrate that infant’s hematopoietic cells seem to respond with more sensitivity to environmental exposure compared to maternal cells.
At least in infants, an activation of these hematopoietic cells by environmental exposure could contribute to an enhanced risk for the development of respiratory outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hörnig, Friederike& Kohajda, Tibor& Röder, Stefan& Herberth, Gunda& von Bergen, Martin& Borte, Michael…[et al.]. 2016. The LINA Study: Higher Sensitivity of Infant Compared to Maternal EosinophilBasophil Progenitors to Indoor Chemical Exposures. Journal of Environmental and Public Health،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108525
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hörnig, Friederike…[et al.]. The LINA Study: Higher Sensitivity of Infant Compared to Maternal EosinophilBasophil Progenitors to Indoor Chemical Exposures. Journal of Environmental and Public Health No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1108525
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hörnig, Friederike& Kohajda, Tibor& Röder, Stefan& Herberth, Gunda& von Bergen, Martin& Borte, Michael…[et al.]. The LINA Study: Higher Sensitivity of Infant Compared to Maternal EosinophilBasophil Progenitors to Indoor Chemical Exposures. Journal of Environmental and Public Health. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1108525
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108525
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر