Depressive and Anxiety Disorders in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations
المؤلفون المشاركون
Xu, Jian
Cheng, Yuqi
Lai, Aiyun
Bai, Ru
Liu, Shuang
Zhao, Yueyin
Li, Shu
Xie, Zhongqi
Xu, Xinyu
Lu, Zhaoping
المصدر
Journal of Immunology Research
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-26
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Depressive and anxiety disorders are frequently observed in patients with Systemic Lupus Erythematosus (SLE).
However, the underlying mechanisms are still unknown.
We conducted this survey to understand the prevalence of depression and anxiety in SLE patients without major neuropsychiatric manifestations (non-NPSLE) and to explore the relationship between emotional disorders, symptoms, autoantibodies, disease activity, and treatments in SLE.
176 SLE patients were included, and SLE disease activity index (SLEDAI), Hamilton Depression Rating Scale (HAMD), and Hamilton Anxiety Rating Scale (HAMA) were recorded to evaluate their disease activity and emotional status.
We found that depressive and anxiety disorders were common among SLE patients: 121 (68.8%) patients were in depression status while 14 (8.0%) patients could be diagnosed with depression.
Accordingly, 101 (57.4%) were in anxiety status and 21 (11.9%) could be diagnosed with anxiety.
Depression was associated with disease activity, and anxiety was associated with anti-P0 antibody, while both of them were associated with proteinuria.
HAMA and HAMD scores were in strong positive correlation and they were independent risk factors of each other.
We concluded that the high prevalence of depression and anxiety and the association between depression and SLE disease activity might reveal the covert damage of central nervous system in SLE.
The role of anti-P0 antibody in SLE patients with emotional disorders warrants more researches.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bai, Ru& Liu, Shuang& Zhao, Yueyin& Cheng, Yuqi& Li, Shu& Lai, Aiyun…[et al.]. 2016. Depressive and Anxiety Disorders in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108745
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bai, Ru…[et al.]. Depressive and Anxiety Disorders in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations. Journal of Immunology Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108745
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bai, Ru& Liu, Shuang& Zhao, Yueyin& Cheng, Yuqi& Li, Shu& Lai, Aiyun…[et al.]. Depressive and Anxiety Disorders in Systemic Lupus Erythematosus Patients without Major Neuropsychiatric Manifestations. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108745
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108745
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر