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Immunomodulatory Effects Mediated by Dopamine
المؤلفون المشاركون
De La Cruz-Aguilera, Dora Luz
Hurtado-Alvarado, Gabriela
Quintero-Fabián, Saray
Becerril, Enrique
Arreola, Rodrigo
Cruz-Fuentes, Carlos
Garcés-Alvarez, María Eugenia
Flores-Gutiérrez, Enrique Octavio
Pérez-Sánchez, Gilberto
Alvarez-Herrera, Samantha
Medina-Rivero, Emilio
Pavon, Lenin
المصدر
Journal of Immunology Research
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-31، 31ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-04
دولة النشر
مصر
عدد الصفحات
31
التخصصات الرئيسية
الملخص EN
Dopamine (DA), a neurotransmitter in the central nervous system (CNS), has modulatory functions at the systemic level.
The peripheral and central nervous systems have independent dopaminergic system (DAS) that share mechanisms and molecular machinery.
In the past century, experimental evidence has accumulated on the proteins knowledge that is involved in the synthesis, reuptake, and transportation of DA in leukocytes and the differential expression of the D1-like (D1R and D5R) and D2-like receptors (D2R, D3R, and D4R).
The expression of these components depends on the state of cellular activation and the concentration and time of exposure to DA.
Receptors that are expressed in leukocytes are linked to signaling pathways that are mediated by changes in cAMP concentration, which in turn triggers changes in phenotype and cellular function.
According to the leukocyte lineage, the effects of DA are associated with such processes as respiratory burst, cytokine and antibody secretion, chemotaxis, apoptosis, and cytotoxicity.
In clinical conditions such as schizophrenia, Parkinson disease, Tourette syndrome, and multiple sclerosis (MS), there are evident alterations during immune responses in leukocytes, in which changes in DA receptor density have been observed.
Several groups have proposed that these findings are useful in establishing clinical status and clinical markers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Arreola, Rodrigo& Alvarez-Herrera, Samantha& Pérez-Sánchez, Gilberto& Becerril, Enrique& Cruz-Fuentes, Carlos& Flores-Gutiérrez, Enrique Octavio…[et al.]. 2016. Immunomodulatory Effects Mediated by Dopamine. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-31.
https://search.emarefa.net/detail/BIM-1108758
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Arreola, Rodrigo…[et al.]. Immunomodulatory Effects Mediated by Dopamine. Journal of Immunology Research No. 2016 (2016), pp.1-31.
https://search.emarefa.net/detail/BIM-1108758
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Arreola, Rodrigo& Alvarez-Herrera, Samantha& Pérez-Sánchez, Gilberto& Becerril, Enrique& Cruz-Fuentes, Carlos& Flores-Gutiérrez, Enrique Octavio…[et al.]. Immunomodulatory Effects Mediated by Dopamine. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-31.
https://search.emarefa.net/detail/BIM-1108758
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108758
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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