Effects of Adoptive Transfer of Tolerogenic Dendritic Cells on Allograft Survival in Organ Transplantation Models: An Overview of Systematic Reviews
المؤلفون المشاركون
Li, You-Ping
Zhou, Yanni
Shan, Juan
Guo, Yingjia
Li, Shengfu
Long, Dan
Feng, Li
المصدر
Journal of Immunology Research
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-28
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Objective.
To dissect the efficacy of Tol-DC therapy with or without IS in multiple animal models of transplantation.
Methods and Results.
PubMed, Medline, Embase, and the Cochrane Library were searched for reviews published up to April 2015.
Six systematic reviews and a total of 61 articles were finally included.
Data were grouped by organ transplantation models and applied to meta-analysis.
Our meta-analysis shows that Tol-DC therapy successfully prolonged allograft survival to varying extents in all except the islet transplantation models and with IS drugs further prolonged the survival of heart, skin, and islet allografts in mice, but not of heart allografts in rats.
Compared with IS drugs alone, Tol-DC therapy with IS extended islet allograft survival in rats but failed to influence the survival of skin, small intestine, and heart allografts in rats or of heart and skin allografts in mice.
Conclusion.
Tol-DC therapy significantly prolonged multiple allograft survival and further prolonged survival with IS.
However, standardized protocols for modification of Tol-DC should be established before its application in clinic.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Yanni& Shan, Juan& Guo, Yingjia& Li, Shengfu& Long, Dan& Li, You-Ping…[et al.]. 2016. Effects of Adoptive Transfer of Tolerogenic Dendritic Cells on Allograft Survival in Organ Transplantation Models: An Overview of Systematic Reviews. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-17.
https://search.emarefa.net/detail/BIM-1108832
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Yanni…[et al.]. Effects of Adoptive Transfer of Tolerogenic Dendritic Cells on Allograft Survival in Organ Transplantation Models: An Overview of Systematic Reviews. Journal of Immunology Research No. 2016 (2016), pp.1-17.
https://search.emarefa.net/detail/BIM-1108832
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Yanni& Shan, Juan& Guo, Yingjia& Li, Shengfu& Long, Dan& Li, You-Ping…[et al.]. Effects of Adoptive Transfer of Tolerogenic Dendritic Cells on Allograft Survival in Organ Transplantation Models: An Overview of Systematic Reviews. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-17.
https://search.emarefa.net/detail/BIM-1108832
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108832
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر