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Clinicopathological Profile of Pure Neuroendocrine Neoplasms of the Esophagus: A South Indian Center Experience
المؤلفون المشاركون
Jacob, Linu A.
Lokanatha, D.
Babu, Govind
Babu, Suresh
Kumar, Rekha V.
Lokesh, K. N.
Lakshmaiah, Kuntegowdanahalli Chinnagiriyappa
Kamath, Mangesh
Rajeev, Lakkavalli Krishnappa
Haleshappa, Rudresha Antapura
Saldanha, Smitha Carol
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
Neuroendocrine neoplasms (NENs) of the esophagus are very uncommon with only a few studies published worldwide.
Studies on clinical profile, management, and outcomes are very uncommon.
Methods.
We report the largest single institution retrospective review of 43 patients of pure esophageal NENs out of our registry of gastrointestinal neuroendocrine tumors treated between 2005 and 2014.
Data on the incidence, tumor location, clinical symptoms, stage at presentation, grading, treatment protocol, and treatment outcomes was collected and analyzed.
Results.
Among 1293 cases of esophageal cancers, pure esophageal NENs were diagnosed in 43 cases.
The mean patient age was 55.8 years.
The male : female ratio was 1.5 : 1.
81.4% of the tumors were located in the lower third of the esophagus and gastroesophageal junction.
Neuroendocrine carcinomas (NEC; G3) accounted for the vast majority of NENs (83.7%).
53.5% patients were Stage IV and 32.5% were Stage III at presentation.
The combined median survival of stages II and III patients was 18.25 months, with treatment.
The median survival of treated patients with metastatic disease was 6.5 months.
Conclusion.
Esophageal NENs most commonly were neuroendocrine carcinomas, presented in metastatic stage and were associated with poor prognosis.
Grade 2 (G2) tumors had better outcomes than NEC (G3).
In nonmetastatic disease, presence of lymph node metastasis and unresectable disease had poorer outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Babu, Govind& Lokanatha, D.& Lakshmaiah, Kuntegowdanahalli Chinnagiriyappa& Kamath, Mangesh& Jacob, Linu A.& Babu, Suresh…[et al.]. 2016. Clinicopathological Profile of Pure Neuroendocrine Neoplasms of the Esophagus: A South Indian Center Experience. Journal of Oncology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109690
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Babu, Govind…[et al.]. Clinicopathological Profile of Pure Neuroendocrine Neoplasms of the Esophagus: A South Indian Center Experience. Journal of Oncology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1109690
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Babu, Govind& Lokanatha, D.& Lakshmaiah, Kuntegowdanahalli Chinnagiriyappa& Kamath, Mangesh& Jacob, Linu A.& Babu, Suresh…[et al.]. Clinicopathological Profile of Pure Neuroendocrine Neoplasms of the Esophagus: A South Indian Center Experience. Journal of Oncology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1109690
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1109690
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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