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Antimicrobial Activity of Croton macrostachyus Stem Bark Extracts against Several Human Pathogenic Bacteria
المؤلفون المشاركون
von Wright, Atte
Obey, Jackie K.
Orjala, Jimmy
Tikkanen-Kaukanen, Carina
Kauhanen, Jussi
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-11
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
In Kenya, leaves and roots from Croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles, but reports on possible antimicrobial activity of stem bark do not exist.
In this study, the antibacterial and antifungal effects of methanol, ethyl acetate and butanol extracts, and purified lupeol of C.
macrostachyus stem bark were determined against important human gram-negative pathogens Escherichia coli, Salmonella typhi, Klebsiella pneumoniae, and Enterobacter aerogenes, gram-positive Listeria monocytogenes, and a fungus Candida albicans.
The most promising broad scale antimicrobial activity against all the studied pathogens was shown by the ethyl acetate extract.
The ethyl acetate extract induced the zone of inhibition between 10.1 ± 0.6 mm and 16.0 ± 1.2 mm against S.
typhi, E.
coli, K.
pneumoniae, E.
aerogenes, and L.
monocytogenes with weaker antimicrobial activity against C.
albicans (zone of inhibition: 5.6 ± 1.0 mm).
The antibiotic controls (amoxicillin, ciprofloxacin, ampicillin, benzylpenicillin, clotrimazole, and cefotaxime) showed antimicrobial activity with zones of inhibition within 13.4 ± 0.7 – 22.1 ± 0.9 mm.
The ethyl acetate extract had MIC in the range of 125–250 mg/mL against all the studied bacteria and against C.
albicans MIC was 500 mg/mL.
The present results give scientific evidence and support the traditional use of C.
macrostachyus stem bark as a source for antimicrobials.
We show that C.
macrostachyus stem bark lupeol is a promising antimicrobial agent against several important human pathogens.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Obey, Jackie K.& von Wright, Atte& Orjala, Jimmy& Kauhanen, Jussi& Tikkanen-Kaukanen, Carina. 2016. Antimicrobial Activity of Croton macrostachyus Stem Bark Extracts against Several Human Pathogenic Bacteria. Journal of Pathogens،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110197
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Obey, Jackie K.…[et al.]. Antimicrobial Activity of Croton macrostachyus Stem Bark Extracts against Several Human Pathogenic Bacteria. Journal of Pathogens No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1110197
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Obey, Jackie K.& von Wright, Atte& Orjala, Jimmy& Kauhanen, Jussi& Tikkanen-Kaukanen, Carina. Antimicrobial Activity of Croton macrostachyus Stem Bark Extracts against Several Human Pathogenic Bacteria. Journal of Pathogens. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1110197
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110197
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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