The Relationship between Population T4TSH Set Point Data and T4TSH Physiology
المؤلفون المشاركون
Fitzgerald, Stephen Paul
Bean, Nigel Geoffrey
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-31
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Context.
Population studies of the distribution of T4/TSH set points suggest a more complex inverse relationship between T4 and TSH than that suggested by physiological studies.
The reasons for the similarities and differences between the curves describing these relationships are unresolved.
Methods.
We subjected the curve, derived from empiric data, describing the TSH suppression response to T4, and the more mathematically derived curve describing the T4 response to TSH, to the different possible models of population variation.
The implied consequences of these in terms of generating a population distribution of T4/TSH equilibrium points (a “population curve”) were generated and compared to the empiric population curve.
The physiological responses to primary hypothyroidism and hyperthyroidism were incorporated into the analysis.
Conclusions.
Though the population curve shows a similarly inverse relationship, it is describing a different relationship than the curve describing the suppression of TSH by T4.
The population curve is consistent with the physiological studies of the TSH response to T4 and implies a greater interindividual variation in the positive thyroid T4 response to TSH than in the central inhibitory TSH response to T4.
The population curve in the dysthyroid states is consistent with known physiological responses to these states.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fitzgerald, Stephen Paul& Bean, Nigel Geoffrey. 2016. The Relationship between Population T4TSH Set Point Data and T4TSH Physiology. Journal of Thyroid Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110879
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fitzgerald, Stephen Paul& Bean, Nigel Geoffrey. The Relationship between Population T4TSH Set Point Data and T4TSH Physiology. Journal of Thyroid Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1110879
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fitzgerald, Stephen Paul& Bean, Nigel Geoffrey. The Relationship between Population T4TSH Set Point Data and T4TSH Physiology. Journal of Thyroid Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110879
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110879
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر