Prenatal Exposures to Multiple Thyroid Hormone Disruptors: Effects on Glucose and Lipid Metabolism
المؤلفون المشاركون
Nitert, Marloes Dekker
Richard, Kerry
Molehin, Deborah
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-17
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Background.
Thyroid hormones (THs) are essential for normal human fetal development and play a major role in the regulation of glucose and lipid metabolism.
Delivery of TH to target tissues is dependent on processes including TH synthesis, transport, and metabolism.
Thyroid hormone endocrine disruptors (TH-EDCs) are chemical substances that interfere with these processes, potentially leading to adverse pregnancy outcomes.
Objectives.
This review focuses on the effects of prenatal exposures to combinations of TH-EDCs on fetal and neonatal glucose and lipid metabolism and also discusses the various mechanisms by which TH-EDCs interfere with other hormonal pathways.
Methods.
We conducted a comprehensive narrative review on the effects of TH-EDCs with particular emphasis on exposure during pregnancy.
Discussion.
TH imbalance has been linked to many metabolic processes and the effects of TH imbalance are particularly pronounced in early fetal development due to fetal dependence on maternal TH for proper growth and development.
The pervasive presence of EDCs in the environment results in ubiquitous exposure to either single or mixtures of EDCs with deleterious effects on metabolism.
Conclusions.
Further evaluation of combined effects of TH-EDCs on fetal metabolic endpoints could improve advice provided to expectant mothers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Molehin, Deborah& Nitert, Marloes Dekker& Richard, Kerry. 2016. Prenatal Exposures to Multiple Thyroid Hormone Disruptors: Effects on Glucose and Lipid Metabolism. Journal of Thyroid Research،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1110883
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Molehin, Deborah…[et al.]. Prenatal Exposures to Multiple Thyroid Hormone Disruptors: Effects on Glucose and Lipid Metabolism. Journal of Thyroid Research No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1110883
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Molehin, Deborah& Nitert, Marloes Dekker& Richard, Kerry. Prenatal Exposures to Multiple Thyroid Hormone Disruptors: Effects on Glucose and Lipid Metabolism. Journal of Thyroid Research. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1110883
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110883
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر