Change in Practice over Four Decades in the Management of Graves’ Disease in Scotland
المؤلفون المشاركون
Thaha, M. A.
Smith, D. M.
Dutta, S.
Ahmed, F.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
There is continuing debate on the optimal treatment for Grave’s thyrotoxicosis with a resultant variation in clinical practice.
The present study aimed to ascertain changes in practice in the treatment of Grave’s thyrotoxicosis in Tayside, Scotland, over the past four decades.
Methods.
The “Scottish automated follow-up register” (SAFUR) was queried to identify all patients treated for Grave’s thyrotoxicosis from 1968 to 2007 inclusive.
Patients were divided into 4 groups (Groups A to D) according to the decades.
Demographic profile, treatment modalities, radioactive iodine (RAI) dose, and recurrence rates were studied and outcomes were compared by χ 2 test and ANOVA using SPSS v15.0.
A p value of < 0.05 was considered significant.
Results.
Altogether, 3737 patients were diagnosed with Grave’s thyrotoxicosis over the 4 decades.
Use of RAI has increased from 43.1% in Group A to 68% in Group D ( p < 0.001 ).
The dose of RAI has increased ( p < 0.001 ) and there has been a reduction in recurrence rate with higher dose of RAI.
Surgical intervention rates decreased from 55.3% to 12.3% ( p < 0.001 ) over time.
Conclusions.
Analysis of a large dataset of patients with Grave’s thyrotoxicosis suggests increasing use of RAI as the preferred first line of treatment.
Furthermore, using a single higher dose of RAI and adoption of total thyroidectomy have decreased recurrence rates.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Smith, D. M.& Dutta, S.& Ahmed, F.& Thaha, M. A.. 2016. Change in Practice over Four Decades in the Management of Graves’ Disease in Scotland. Journal of Thyroid Research،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110885
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Smith, D. M.…[et al.]. Change in Practice over Four Decades in the Management of Graves’ Disease in Scotland. Journal of Thyroid Research No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1110885
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Smith, D. M.& Dutta, S.& Ahmed, F.& Thaha, M. A.. Change in Practice over Four Decades in the Management of Graves’ Disease in Scotland. Journal of Thyroid Research. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110885
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110885
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر