NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula

المؤلفون المشاركون

Gong, Chenyuan
Luo, Yingbin
Wu, Jianchun
Zhu, Xiaowen
Yao, Chao
Ni, Zhongya
Wang, Lixin
Ni, Lulu
Li, Yan
Zhu, Shiguo

المصدر

Mediators of Inflammation

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-02-29

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأمراض

الملخص EN

Little is known about Yu-Ping-Feng (YPF), a typical Chinese herbal decoction, for its antitumor efficacy in non-small-cell lung cancer (NSCLC).

Here, we found that YPF significantly inhibited the growth of Lewis lung cancer, prolonged the survival of tumor-bearing mice, promoted NK cell tumor infiltration, increased the population of NK cells in spleen, and enhanced NK cell-mediated killing activity.

The growth suppression of tumors by YPF was significantly reversed by the depletion of NK cells.

Furthermore, we found that YPF significantly downregulated the expression of TGF-β, indoleamine 2,3-dioxygenase, and IL-10 in tumor microenvironment.

These results demonstrated that YPF has a NK cell-dependent inhibitory effect on Lewis lung cancer.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Luo, Yingbin& Wu, Jianchun& Zhu, Xiaowen& Gong, Chenyuan& Yao, Chao& Ni, Zhongya…[et al.]. 2016. NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1111016

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Luo, Yingbin…[et al.]. NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula. Mediators of Inflammation No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1111016

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Luo, Yingbin& Wu, Jianchun& Zhu, Xiaowen& Gong, Chenyuan& Yao, Chao& Ni, Zhongya…[et al.]. NK Cell-Dependent Growth Inhibition of Lewis Lung Cancer by Yu-Ping-Feng, an Ancient Chinese Herbal Formula. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1111016

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1111016