Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease
المؤلفون المشاركون
Carvajal, Karla
Phillips-Farfán, Bryan
Medina-Torres, Edgar Alejandro
Espinosa-Padilla, Sara Elva
Fabrias, Gemma
Camacho, Luz
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-30
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Inflammatory bowel disease (IBD) describes different illnesses characterized by chronic inflammation of the gastrointestinal tract.
Although the pathogenic mechanisms leading to IBD are poorly understood, immune system disturbances likely underlie its development.
Sphingolipids (SLs) have been identified as important players and promising therapeutic targets to control inflammation in IBD.
Interestingly, it seems that microorganisms of the normal gut microbiota and probiotics are involved in sphingolipid function.
However, there is a great need to investigate the role of SLs as intermediates in the crosstalk between intestinal immunity and microorganisms.
This review focuses on recent investigations that describe some mechanisms involved in the regulation of cytokine profiles by SLs.
We also describe the importance of gut microbiota in providing signaling molecules that favor the communication between resident bacteria and intestinal cells.
This, in turn, modulates the immune response in the bowel and likely in other peripheral organs.
The potential of SLs and gut microbiota as targets or therapeutic agents for IBD is also discussed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Phillips-Farfán, Bryan& Carvajal, Karla& Medina-Torres, Edgar Alejandro& Espinosa-Padilla, Sara Elva& Fabrias, Gemma& Camacho, Luz. 2016. Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1111338
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Phillips-Farfán, Bryan…[et al.]. Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease. Mediators of Inflammation No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1111338
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Phillips-Farfán, Bryan& Carvajal, Karla& Medina-Torres, Edgar Alejandro& Espinosa-Padilla, Sara Elva& Fabrias, Gemma& Camacho, Luz. Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1111338
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1111338
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر