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Synchronized Progression of Prestin Expression and Auditory Brainstem Response during Postnatal Development in Rats
المؤلفون المشاركون
Fu, Mingyu
Tang, Jie
Hang, Jianfeng
Pan, Wenlu
Chang, Aoshuang
Li, Shun
Li, Cuixian
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-21
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Prestin is the motor protein expressed in the cochlear outer hair cells (OHCs) of mammalian inner ear.
The electromotility of OHCs driven by prestin is responsible for the cochlear amplification which is required for normal hearing in adult animals.
Postnatal expression of prestin and activity of OHCs may contribute to the maturation of hearing in rodents.
However, the temporal and spatial expression of prestin in cochlea during the development is not well characterized.
In the present study, we examined the expression and function of prestin from the OHCs in apical, middle, and basal turns of the cochleae of postnatal rats.
Prestin first appeared at postnatal day 6 (P6) for basal turn, P7 in middle turn, and P9 for apical turn of cochlea.
The expression level increased progressively over the next few days and by P14 reached the mature level for all three segments.
By comparison with the time course of the development of auditory brainstem response for different frequencies, our data reveal that prestin expression synchronized with the hearing development.
The present study suggests that the onset time of hearing may require the expression of prestin and is determined by the mature function of OHCs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hang, Jianfeng& Pan, Wenlu& Chang, Aoshuang& Li, Shun& Li, Cuixian& Fu, Mingyu…[et al.]. 2016. Synchronized Progression of Prestin Expression and Auditory Brainstem Response during Postnatal Development in Rats. Neural Plasticity،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1113147
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hang, Jianfeng…[et al.]. Synchronized Progression of Prestin Expression and Auditory Brainstem Response during Postnatal Development in Rats. Neural Plasticity No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1113147
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hang, Jianfeng& Pan, Wenlu& Chang, Aoshuang& Li, Shun& Li, Cuixian& Fu, Mingyu…[et al.]. Synchronized Progression of Prestin Expression and Auditory Brainstem Response during Postnatal Development in Rats. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1113147
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113147
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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