Electroacupuncture Reduces the Effects of Acute Noxious Stimulation on the Electrical Activity of Pain-Related Neurons in the Hippocampus of Control and Neuropathic Pain Rats
المؤلفون المشاركون
Chen, Shuping
Feng, Xiumei
Yan, Yaxia
Liu, Junling
Chen, Renbo
Lippe, Irmgard Th.
Litscher, Daniela
Wang, Lu
Litscher, Gerhard
Zhang, Jian-liang
Gao, Yong-hui
Gaischek, Ingrid
Wang, Jun-ying
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-19
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
To study the effects of acupuncture analgesia on the hippocampus, we observed the effects of electroacupuncture (EA) and mitogen-activated protein kinase (MEK) inhibitor on pain-excited neurons (PENs) and pain-inhibited neurons (PINs) in the hippocampal area CA1 of sham or chronic constrictive injury (CCI) rats.
The animals were randomly divided into a control, a CCI, and a U0126 (MEK1/2 inhibitor) group.
In all experiments, we briefly (10-second duration) stimulated the sciatic nerve electrically and recorded the firing rates of PENs and PINs.
The results showed that in both sham and CCI rats brief sciatic nerve stimulation significantly increased the electrical activity of PENs and markedly decreased the electrical activity of PINs.
These effects were significantly greater in CCI rats compared to sham rats.
EA treatment reduced the effects of the noxious stimulus on PENs and PINs in both sham and CCI rats.
The effects of EA treatment could be inhibited by U0126 in sham-operated rats.
The results suggest that EA reduces effects of acute sciatic nerve stimulation on PENs and PINs in the CA1 region of the hippocampus of both sham and CCI rats and that the ERK (extracellular regulated kinase) signaling pathway is involved in the modulation of EA analgesia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Jun-ying& Chen, Renbo& Chen, Shuping& Gao, Yong-hui& Zhang, Jian-liang& Feng, Xiumei…[et al.]. 2016. Electroacupuncture Reduces the Effects of Acute Noxious Stimulation on the Electrical Activity of Pain-Related Neurons in the Hippocampus of Control and Neuropathic Pain Rats. Neural Plasticity،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113231
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Jun-ying…[et al.]. Electroacupuncture Reduces the Effects of Acute Noxious Stimulation on the Electrical Activity of Pain-Related Neurons in the Hippocampus of Control and Neuropathic Pain Rats. Neural Plasticity No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1113231
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Jun-ying& Chen, Renbo& Chen, Shuping& Gao, Yong-hui& Zhang, Jian-liang& Feng, Xiumei…[et al.]. Electroacupuncture Reduces the Effects of Acute Noxious Stimulation on the Electrical Activity of Pain-Related Neurons in the Hippocampus of Control and Neuropathic Pain Rats. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113231
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113231
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر