Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome

المؤلفون المشاركون

Zhao, Huan
Yang, Tao
Lu, Changbo
Li, Xiaoyu
Xie, Yingli
Fu, Hao
Xu, Hui

المصدر

Neural Plasticity

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-04-28

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الأحياء
الطب البشري

الملخص EN

Fragile X syndrome (FXS) is an inheritable neuropsychological disease caused by expansion of the CGG trinucleotide repeat affecting the fmr1 gene on X chromosome, resulting in silence of the fmr1 gene and failed expression of FMRP.

Patients with FXS suffer from cognitive impairment, sensory integration deficits, learning disability, anxiety, autistic traits, and so forth.

Specifically, the morbidity of anxiety in FXS individuals remains high from childhood to adulthood.

By and large, it is common that the change of brain plasticity plays a key role in the progression of disease.

But for now, most studies excessively emphasized the one-sided factor on the change of synaptic plasticity participating in the generation of anxiety during the development of FXS.

Here we proposed an integrated concept to acquire better recognition about the details of this process.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Yang, Tao& Zhao, Huan& Lu, Changbo& Li, Xiaoyu& Xie, Yingli& Fu, Hao…[et al.]. 2016. Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome. Neural Plasticity،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1113382

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Yang, Tao…[et al.]. Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome. Neural Plasticity No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1113382

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Yang, Tao& Zhao, Huan& Lu, Changbo& Li, Xiaoyu& Xie, Yingli& Fu, Hao…[et al.]. Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1113382

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1113382