Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome
Joint Authors
Zhao, Huan
Yang, Tao
Lu, Changbo
Li, Xiaoyu
Xie, Yingli
Fu, Hao
Xu, Hui
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-28
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Fragile X syndrome (FXS) is an inheritable neuropsychological disease caused by expansion of the CGG trinucleotide repeat affecting the fmr1 gene on X chromosome, resulting in silence of the fmr1 gene and failed expression of FMRP.
Patients with FXS suffer from cognitive impairment, sensory integration deficits, learning disability, anxiety, autistic traits, and so forth.
Specifically, the morbidity of anxiety in FXS individuals remains high from childhood to adulthood.
By and large, it is common that the change of brain plasticity plays a key role in the progression of disease.
But for now, most studies excessively emphasized the one-sided factor on the change of synaptic plasticity participating in the generation of anxiety during the development of FXS.
Here we proposed an integrated concept to acquire better recognition about the details of this process.
American Psychological Association (APA)
Yang, Tao& Zhao, Huan& Lu, Changbo& Li, Xiaoyu& Xie, Yingli& Fu, Hao…[et al.]. 2016. Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome. Neural Plasticity،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1113382
Modern Language Association (MLA)
Yang, Tao…[et al.]. Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome. Neural Plasticity No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1113382
American Medical Association (AMA)
Yang, Tao& Zhao, Huan& Lu, Changbo& Li, Xiaoyu& Xie, Yingli& Fu, Hao…[et al.]. Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1113382
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113382