Comparison of Human Papillomavirus Detection in Urine and Cervical Samples Using High-Risk HPV DNA Testing in Northern Thailand
المؤلفون المشاركون
Settakorn, Jongkolnee
Sukpan, Kornkanok
Siriaunkgul, Sumalee
Lekawanvijit, Suree
Katruang, Narisara
Khunamornpong, Surapan
المصدر
Obstetrics and Gynecology International
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
To evaluate the performance of high-risk human papillomavirus (HPV) DNA testing in urine samples compared to that of cervical sample testing in Northern Thailand.
Methods.
Paired urine and cervical samples were collected during the follow-up of women with a previous positive HPV test.
HPV testing was performed using the Cobas 4800 HPV Test.
Linear Array assay was used for genotyping in selected cases.
Results.
Paired urine and cervical samples were obtained from 168 women.
Of 123 paired samples with valid results, agreement in the detection of high-risk HPV DNA was present in 106 cases (86.2%), with a kappa statistic of 0.65 (substantial agreement).
Using the cervical HPV results as a reference, the sensitivity of urine HPV testing was 68.6% (24/35) and the specificity 93.2% (82/88).
For the detection of histologic high-grade squamous intraepithelial lesion or worse (HSIL+), the sensitivity of urine HPV testing was 80.0% (4/5) and the specificity 78.0% (92/118).
Conclusion.
Although urine HPV testing had a rather low sensitivity for HPV detection, its sensitivity for histologic HSIL+ detection was high.
For clinical use of urine HPV testing, standardization of specimen collection and processing techniques or application of a more sensitive test, especially in the detection of HPV52 and HPV58, is necessary.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khunamornpong, Surapan& Settakorn, Jongkolnee& Sukpan, Kornkanok& Lekawanvijit, Suree& Katruang, Narisara& Siriaunkgul, Sumalee. 2016. Comparison of Human Papillomavirus Detection in Urine and Cervical Samples Using High-Risk HPV DNA Testing in Northern Thailand. Obstetrics and Gynecology International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113505
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khunamornpong, Surapan…[et al.]. Comparison of Human Papillomavirus Detection in Urine and Cervical Samples Using High-Risk HPV DNA Testing in Northern Thailand. Obstetrics and Gynecology International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1113505
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khunamornpong, Surapan& Settakorn, Jongkolnee& Sukpan, Kornkanok& Lekawanvijit, Suree& Katruang, Narisara& Siriaunkgul, Sumalee. Comparison of Human Papillomavirus Detection in Urine and Cervical Samples Using High-Risk HPV DNA Testing in Northern Thailand. Obstetrics and Gynecology International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113505
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113505
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر