Effect of High-Intensity Training in Normobaric Hypoxia on Thoroughbred Skeletal Muscle
المؤلفون المشاركون
Nagahisa, Hiroshi
Mukai, Kazutaka
Ohmura, Hajime
Takahashi, Toshiyuki
Miyata, Hirofumi
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-19
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Hypoxic training is believed to increase endurance capacity in association with hypoxia inducible factor-1α (HIF-1α), a modulator of vascular endothelial growth factor-A (VEGF-A), and to influence activation of satellite cells (SCs).
However, the effect of hypoxic training on SC activation and its relation to angiogenesis has not been thoroughly investigated.
Eight Thoroughbred horses were subjected to normoxic ( F I O 2 = 21%) or hypoxic ( F I O 2 = 15%) training for 3 days/week (100% V ˙ O 2 m a x ) for 4 weeks.
Incremental exercise tests (IET) were conducted on a treadmill under normoxia and the maximal oxygen consumption ( V ˙ O 2 m a x ) and running distance were measured before and after each training session.
Muscle biopsy samples were obtained from the gluteus medius muscle at 6 scheduled times before, during, and one week after IET for immunohistochemical analysis and real-time RT-PCR analysis.
Running distance and V ˙ O 2 m a x , measured during IET, increased significantly after hypoxic training compared with normoxic training.
Capillary density and mRNA expression related to SC activation (e.g., myogenin and hepatocyte growth factor) and angiogenesis (VEGF-A) increased only after hypoxic training.
These results suggest that increases in mRNA expression after training enhance and prolong SC activation and angiogenesis and that nitric oxide plays an important role in these hypoxia-induced training effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nagahisa, Hiroshi& Mukai, Kazutaka& Ohmura, Hajime& Takahashi, Toshiyuki& Miyata, Hirofumi. 2016. Effect of High-Intensity Training in Normobaric Hypoxia on Thoroughbred Skeletal Muscle. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1113624
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nagahisa, Hiroshi…[et al.]. Effect of High-Intensity Training in Normobaric Hypoxia on Thoroughbred Skeletal Muscle. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1113624
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nagahisa, Hiroshi& Mukai, Kazutaka& Ohmura, Hajime& Takahashi, Toshiyuki& Miyata, Hirofumi. Effect of High-Intensity Training in Normobaric Hypoxia on Thoroughbred Skeletal Muscle. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1113624
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113624
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر