Neurobehavioral and Antioxidant Effects of Ethanolic Extract of Yellow Propolis
المؤلفون المشاركون
Monteiro, Marta Chagas
Torres, Yohandra Reyes
Machado, Christiane Schineider
Lira, Tatiana Onofre de
Ferreira, Antonio Gilberto
Fontes-Júnior, Enéas Andrade
Maia, Cristiane Socorro Ferraz
Fernandes, Luanna Melo Pereira
da Silveira, Cinthia Cristina Sousa de Menezes
Silva, Mallone Lopes
Luz, Diandra Araújo
Gomes, Antônio Rafael Quadros
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-16
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Propolis is a resin produced by bees from raw material collected from plants, salivary secretions, and beeswax.
New therapeutic properties for the Central Nervous System have emerged.
We explored the neurobehavioral and antioxidant effects of an ethanolic extract of yellow propolis (EEYP) rich in triterpenoids, primarily lupeol and β-amyrin.
Male Wistar rats, 3 months old, were intraperitoneally treated with Tween 5% (control), EEYP (1, 3, 10, and 30 mg/kg), or diazepam, fluoxetine, and caffeine (positive controls) 30 min before the assays.
Animals were submitted to open field, elevated plus maze, forced swimming, and inhibitory avoidance tests.
After behavioral tasks, blood samples were collected through intracardiac pathway, to evaluate the oxidative balance.
The results obtained in the open field and in the elevated plus maze assay showed spontaneous locomotion preserved and anxiolytic-like activity.
In the forced swimming test, EEYP demonstrated antidepressant-like activity.
In the inhibitory avoidance test, EEYP showed mnemonic activity at 30 mg/kg.
In the evaluation of oxidative biochemistry, the extract reduced the production of nitric oxide and malondialdehyde without changing level of total antioxidant, catalase, and superoxide dismutase, induced by behavioral stress.
Our results highlight that EEYP emerges as a promising anxiolytic, antidepressant, mnemonic, and antioxidant natural product.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
da Silveira, Cinthia Cristina Sousa de Menezes& Fernandes, Luanna Melo Pereira& Silva, Mallone Lopes& Luz, Diandra Araújo& Gomes, Antônio Rafael Quadros& Monteiro, Marta Chagas…[et al.]. 2016. Neurobehavioral and Antioxidant Effects of Ethanolic Extract of Yellow Propolis. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1113752
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
da Silveira, Cinthia Cristina Sousa de Menezes…[et al.]. Neurobehavioral and Antioxidant Effects of Ethanolic Extract of Yellow Propolis. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1113752
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
da Silveira, Cinthia Cristina Sousa de Menezes& Fernandes, Luanna Melo Pereira& Silva, Mallone Lopes& Luz, Diandra Araújo& Gomes, Antônio Rafael Quadros& Monteiro, Marta Chagas…[et al.]. Neurobehavioral and Antioxidant Effects of Ethanolic Extract of Yellow Propolis. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1113752
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113752
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر