Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches

المؤلفون المشاركون

Balmus, Ioana Miruna
Ciobica, Alin
Antioch, Iulia
Dobrin, Romeo
Timofte, Daniel

المصدر

Oxidative Medicine and Cellular Longevity

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-25، 25ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-08-01

دولة النشر

مصر

عدد الصفحات

25

التخصصات الرئيسية

الأحياء

الملخص EN

The correlation between the affective disorders and the almost ubiquitous pathological oxidative stress can be described in a multifactorial way, as an important mechanism of central nervous system impairment.

Whether the obvious changes which occur in oxidative balance of the affective disorders are a part of the constitutive mechanism or a collateral effect yet remains as an interesting question.

However it is now clear that oxidative stress is a component of these disorders, being characterized by different aspects in a disease-dependent manner.

Still, there are a lot of controversies regarding the relevance of the oxidative stress status in most of the affective disorders and despite the fact that most of the studies are showing that the affective disorders development can be correlated to increased oxidative levels, there are various studies stating that oxidative stress is not linked with the mood changing tendencies.

Thus, in this minireview we decided to describe the way in which oxidative stress is involved in the affective disorders development, by focusing on the main oxidative stress markers that could be used mechanistically and therapeutically in these deficiencies, the genetic perspectives, some antioxidant approaches, and the relevance of some animal models studies in this context.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Balmus, Ioana Miruna& Ciobica, Alin& Antioch, Iulia& Dobrin, Romeo& Timofte, Daniel. 2016. Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-25.
https://search.emarefa.net/detail/BIM-1113885

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Balmus, Ioana Miruna…[et al.]. Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-25.
https://search.emarefa.net/detail/BIM-1113885

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Balmus, Ioana Miruna& Ciobica, Alin& Antioch, Iulia& Dobrin, Romeo& Timofte, Daniel. Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-25.
https://search.emarefa.net/detail/BIM-1113885

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1113885