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Memory Deficit Recovery after Chronic Vanadium Exposure in Mice
المؤلفون المشاركون
Olopade, James Olukayode
Folarin, Oluwabusayo
Olopade, Funmilayo
Onwuka, Silas
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Vanadium is a transitional metal with an ability to generate reactive oxygen species in the biological system.
This work was designed to assess memory deficits in mice chronically exposed to vanadium.
A total of 132 male BALB/c mice (4 weeks old) were used for the experiment and were divided into three major groups of vanadium treated, matched controls, and animals exposed to vanadium for three months and thereafter vanadium was withdrawn.
Animals were tested using Morris water maze and forelimb grip test at 3, 6, 9, and 12 months of age.
The results showed that animals across the groups showed no difference in learning but had significant loss in memory abilities after 3 months of vanadium exposure and this trend continued in all vanadium-exposed groups relative to the controls.
Animals exposed to vanadium for three months recovered significantly only 9 months after vanadium withdrawal.
There was no significant difference in latency to fall in the forelimb grip test between vanadium-exposed groups and the controls in all age groups.
In conclusion, we have shown that chronic administration of vanadium in mice leads to memory deficit which is reversible but only after a long period of vanadium withdrawal.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Folarin, Oluwabusayo& Olopade, Funmilayo& Onwuka, Silas& Olopade, James Olukayode. 2016. Memory Deficit Recovery after Chronic Vanadium Exposure in Mice. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1113969
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Folarin, Oluwabusayo…[et al.]. Memory Deficit Recovery after Chronic Vanadium Exposure in Mice. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1113969
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Folarin, Oluwabusayo& Olopade, Funmilayo& Onwuka, Silas& Olopade, James Olukayode. Memory Deficit Recovery after Chronic Vanadium Exposure in Mice. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1113969
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113969
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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