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Metabolic Syndrome Augments the Risk of Early Neurological Deterioration in Acute Ischemic Stroke Patients Independent of Inflammatory Mediators: A Hospital-Based Prospective Study
المؤلفون المشاركون
Xie, Yi
Zhang, Xiaohao
Sun, Zhiguang
Ding, Caixia
Tang, Yinyan
Jiang, Xuemei
Li, Chuanyou
Zhang, Lankun
Hu, Dan
Li, Tingting
Xu, Gelin
Sheng, Lei
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background and Aims.
Metabolic syndrome (MetS) has been associated with occurrence and prognosis of ischemic stroke.
This study aimed to evaluate whether an association exists between MetS and early neurological deterioration (END) following acute ischemic stroke and the possible role inflammatory biomarkers play.
Methods and Results.
We conducted a prospective cohort investigation that involved 208 stroke patients within 48 hours from symptom onset.
MetS was determined by the modified National Cholesterol Education Program/Adult Treatment Panel III criteria.
END was defined as an increase of ⩾1 point in motor power or ⩾2 points in the total National Institutes of Health Stroke Scale (NIHSS) score within 7 days.
Univariate logistic regression analysis showed that patients with MetS had a 125% increased risk of END (OR 2.25; 95% CI 1.71–4.86, P=0.005).
After adjustment for fibrinogen and high-sensitivity C-reactive protein, MetS remained significantly correlated to END (OR 2.20; 95% CI 1.10–4.04, P=0.026) with a 77% elevated risk per additional MetS trait (OR 1.77; 95% CI 1.23–2.58, P=0.002).
Conclusions.
This study demonstrated that MetS may be a potential predictor for END after ischemic stroke, which was independent of raised inflammatory mediators.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Xiaohao& Sun, Zhiguang& Ding, Caixia& Tang, Yinyan& Jiang, Xuemei& Xie, Yi…[et al.]. 2016. Metabolic Syndrome Augments the Risk of Early Neurological Deterioration in Acute Ischemic Stroke Patients Independent of Inflammatory Mediators: A Hospital-Based Prospective Study. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1114339
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Xiaohao…[et al.]. Metabolic Syndrome Augments the Risk of Early Neurological Deterioration in Acute Ischemic Stroke Patients Independent of Inflammatory Mediators: A Hospital-Based Prospective Study. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1114339
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Xiaohao& Sun, Zhiguang& Ding, Caixia& Tang, Yinyan& Jiang, Xuemei& Xie, Yi…[et al.]. Metabolic Syndrome Augments the Risk of Early Neurological Deterioration in Acute Ischemic Stroke Patients Independent of Inflammatory Mediators: A Hospital-Based Prospective Study. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1114339
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114339
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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