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Systemic Redox Imbalance in Chronic Kidney Disease: A Systematic Review
المؤلفون المشاركون
Jamurtas, Athanasios Z.
Poulianiti, Konstantina P.
Kaltsatou, Antonia
Mitrou, Georgia I.
Koutedakis, Yiannis
Maridaki, Maria
Stefanidis, Ioannis
Sakkas, Giorgos K.
Karatzaferi, Christina
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-19، 19ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-03
دولة النشر
مصر
عدد الصفحات
19
التخصصات الرئيسية
الملخص EN
Patients with chronic kidney disease (CKD) experience imbalance between oxygen reactive species (ROS) production and antioxidant defenses leading to cell and tissue damage.
However, it remains unclear at which stage of renal insufficiency the redox imbalance becomes more profound.
The aim of this systematic review was to provide an update on recent advances in our understanding of how the redox status changes in the progression of renal disease from predialysis stages 1 to 4 to end stage 5 and whether the various treatments and dialysis modalities influence the redox balance.
A systematic review was conducted searching PubMed and Scopus by using the Cochrane and PRISMA guidelines.
In total, thirty-nine studies met the inclusion criteria and were reviewed.
Even from an early stage, imbalance in redox status is evident and as the kidney function worsens it becomes more profound.
Hemodialysis therapy per se seems to negatively influence the redox status by the elevation of lipid peroxidation markers, protein carbonylation, and impairing erythrocyte antioxidant defense.
However, other dialysis modalities do not so far appear to confer advantages.
Supplementation with antioxidants might assist and should be considered as an early intervention to halt premature atherogenesis development at an early stage of CKD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Poulianiti, Konstantina P.& Kaltsatou, Antonia& Mitrou, Georgia I.& Jamurtas, Athanasios Z.& Koutedakis, Yiannis& Maridaki, Maria…[et al.]. 2016. Systemic Redox Imbalance in Chronic Kidney Disease: A Systematic Review. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-19.
https://search.emarefa.net/detail/BIM-1114403
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Poulianiti, Konstantina P.…[et al.]. Systemic Redox Imbalance in Chronic Kidney Disease: A Systematic Review. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-19.
https://search.emarefa.net/detail/BIM-1114403
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Poulianiti, Konstantina P.& Kaltsatou, Antonia& Mitrou, Georgia I.& Jamurtas, Athanasios Z.& Koutedakis, Yiannis& Maridaki, Maria…[et al.]. Systemic Redox Imbalance in Chronic Kidney Disease: A Systematic Review. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-19.
https://search.emarefa.net/detail/BIM-1114403
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114403
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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