Energy Drink Administration in Combination with Alcohol Causes an Inflammatory Response and Oxidative Stress in the Hippocampus and Temporal Cortex of Rats
المؤلفون المشاركون
Brambila, Eduardo
Guevara, J.
Treviño, Samuel
Díaz, Alfonso
Muñoz-Arenas, Guadalupe
Espinosa, Blanca
Moreno-Rodríguez, Albino
Lopez-Lopez, Gustavo
Peña-Rosas, Ulises
Venegas, Berenice
Handal-Silva, Anabella
Morán-Perales, José Luis
Flores, Gonzalo
Aguilar-Alonso, Patricia
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-16
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Energy drinks (EDs) are often consumed in combination with alcohol because they reduce the depressant effects of alcohol.
However, different researches suggest that chronic use of these psychoactive substances in combination with alcohol can trigger an oxidative and inflammatory response.
These processes are regulated by both a reactive astrogliosis and an increase of proinflammatory cytokines such as IL-1β, TNF-α, and iNOS, causing cell death (apoptosis) at the central and peripheral nervous systems.
Currently, mechanisms of toxicity caused by mixing alcohol and ED in the brain are not well known.
In this study, we evaluated the effect of chronic alcohol consumption in combination with ED on inflammatory response and oxidative stress in the temporal cortex (TCx) and hippocampus (Hp) of adult rats (90 days old).
Our results demonstrated that consuming a mixture of alcohol and ED for 60 days induced an increase in reactive gliosis, IL-1β, TNF-α, iNOS, reactive oxygen species, lipid peroxidation, and nitric oxide, in the TCx and Hp.
We also found immunoreactivity to caspase-3 and a decrease of synaptophysin in the same brain regions.
The results suggested that chronic consumption of alcohol in combination with ED causes an inflammatory response and oxidative stress, which induced cell death via apoptosis in the TCx and Hp of the adult rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Díaz, Alfonso& Treviño, Samuel& Guevara, J.& Muñoz-Arenas, Guadalupe& Brambila, Eduardo& Espinosa, Blanca…[et al.]. 2016. Energy Drink Administration in Combination with Alcohol Causes an Inflammatory Response and Oxidative Stress in the Hippocampus and Temporal Cortex of Rats. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114457
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Díaz, Alfonso…[et al.]. Energy Drink Administration in Combination with Alcohol Causes an Inflammatory Response and Oxidative Stress in the Hippocampus and Temporal Cortex of Rats. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1114457
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Díaz, Alfonso& Treviño, Samuel& Guevara, J.& Muñoz-Arenas, Guadalupe& Brambila, Eduardo& Espinosa, Blanca…[et al.]. Energy Drink Administration in Combination with Alcohol Causes an Inflammatory Response and Oxidative Stress in the Hippocampus and Temporal Cortex of Rats. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114457
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114457
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر