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Effect of Intraperitoneal Etanercept on Oxidative Stress in Rats with Peritonitis
المؤلفون المشاركون
Yılmaz, Zülfükar
Kara, Ali Veysel
Cellad, Esma Gulsum
Gul, Mesut
Ketani, Muzaffer Aydin
Yilmaz, Mehmet Emin
Bahadir, Mehmet Veysi
Yıldırım, Yaşar
Kadiroğlu, Ali Kemal
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-14
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Our aim was to evaluate effect of etanercept on oxidative stress parameters in rats with experimental peritonitis and investigate the availability of etanercept usage in the treatment of peritonitis in the future.
Twenty-eight rats were divided into four groups as control (group 1), peritonitis (group 2), peritonitis + cefazolin sodium (group 3), and peritonitis + cefazolin sodium + etanercept (group 4).
Peritoneal tissue and blood samples were taken from all of the rats for histopathological and biochemical examination.
The oxidative stress parameters were examined in blood and tissue samples.
It was observed that rats with peritonitis benefit from cefazolin sodium treatment.
Evaluating the effectiveness of etanercept was our main objective for this study.
In this perspective, we compared group 3 and group 4 and found statistically significant decreases in oxidative parameters and statistically significant increases in antioxidants in serum and tissue samples in group 4.
It is observed that there was a significant contribution of etanercept on biochemical and also histopathological results.
As a result, the TNF-α inhibitor, etanercept, in addition to antibiotics given in the early treatment of peritonitis results in more significant improvement of histopathological and oxidative parameters as compared to antibiotics alone.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yıldırım, Yaşar& Cellad, Esma Gulsum& Kara, Ali Veysel& Yılmaz, Zülfükar& Kadiroğlu, Ali Kemal& Bahadir, Mehmet Veysi…[et al.]. 2016. Effect of Intraperitoneal Etanercept on Oxidative Stress in Rats with Peritonitis. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1114765
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yıldırım, Yaşar…[et al.]. Effect of Intraperitoneal Etanercept on Oxidative Stress in Rats with Peritonitis. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1114765
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yıldırım, Yaşar& Cellad, Esma Gulsum& Kara, Ali Veysel& Yılmaz, Zülfükar& Kadiroğlu, Ali Kemal& Bahadir, Mehmet Veysi…[et al.]. Effect of Intraperitoneal Etanercept on Oxidative Stress in Rats with Peritonitis. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1114765
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114765
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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