Pelvic Radiotherapy versus Radical Prostatectomy with Limited Lymph Node Sampling for High-Grade Prostate Adenocarcinoma
المؤلفون المشاركون
Nix, Jeffrey W.
Baker, Christopher B.
McDonald, Andrew M.
Yang, Eddy S.
Jacob, Rojymon
Rais-Bahrami, Soroush
Fiveash, John B.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-09
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To compare oncologic outcomes for patients with Gleason score (GS) ≥ 8 prostate adenocarcinoma treated with radical prostatectomy (RP) versus external beam radiotherapy combined with androgen deprivation (RT + ADT).
Methods.
Between 2001 and 2014, 121 patients with GS ≥ 8 were treated at our institution via RT + ADT ( n = 71 ) or RP ( n = 50 ) with ≥ 1 year of biochemical follow-up.
Endpoints included biochemical failure (BF), distant metastasis, and initiation of salvage ADT.
Results.
The RT + ADT group was older, had higher biopsy GS, and had greater risk of lymph node involvement.
All other pretreatment characteristics were similar between groups.
Mean number of lymph nodes (LNs) sampled for patients undergoing RP was 8.2 (±6.18).
Mean biochemical follow-up for all patients was 61 months.
Five-year estimates of BF for the RT + ADT and RP groups were 7.2% versus 42.3%, ( p < 0.001 ).
The RT + ADT group also had lower rates of distant metastasis (2% versus 7.8%) and salvage ADT (8% versus 33.8%).
Conclusion.
In this analysis, RT + ADT was associated with improved biochemical and metastatic control when compared to RP with limited LN sampling.
How RT + ADT compares with more aggressive lymphadenectomy, as is currently our institutional standard, remains an important unanswered question.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Baker, Christopher B.& McDonald, Andrew M.& Yang, Eddy S.& Jacob, Rojymon& Rais-Bahrami, Soroush& Nix, Jeffrey W.…[et al.]. 2016. Pelvic Radiotherapy versus Radical Prostatectomy with Limited Lymph Node Sampling for High-Grade Prostate Adenocarcinoma. Prostate Cancer،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1114889
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Baker, Christopher B.…[et al.]. Pelvic Radiotherapy versus Radical Prostatectomy with Limited Lymph Node Sampling for High-Grade Prostate Adenocarcinoma. Prostate Cancer No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1114889
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Baker, Christopher B.& McDonald, Andrew M.& Yang, Eddy S.& Jacob, Rojymon& Rais-Bahrami, Soroush& Nix, Jeffrey W.…[et al.]. Pelvic Radiotherapy versus Radical Prostatectomy with Limited Lymph Node Sampling for High-Grade Prostate Adenocarcinoma. Prostate Cancer. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1114889
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114889
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر