Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite
المؤلفون المشاركون
Schirmer, Henrik
Sibille, Kimberly T.
Steingrímsdóttir, Ólöf A.
Fillingim, Roger B.
Stubhaug, Audun
Chen, Huaihou
McEwen, Bruce S.
Nielsen, Christopher S.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-02
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Chronic pain is associated with increased morbidity and mortality, predominated by cardiovascular disease and cancer.
Investigating related risk factor measures may elucidate the biological burden of chronic pain.
Objectives.
We hypothesized that chronic pain severity would be positively associated with the risk factor composite.
Methods.
Data from 12,982 participants in the 6th Tromsø study were analyzed.
Questionnaires included demographics, health behaviors, medical comorbidities, and chronic pain symptoms.
The risk factor composite was comprised of body mass index, fibrinogen, C-reactive protein, and triglycerides.
Chronic pain severity was characterized by frequency, intensity, time/duration, and total number of pain sites.
Results.
Individuals with chronic pain had a greater risk factor composite than individuals without chronic pain controlling for covariates and after excluding inflammation-related health conditions ( p < 0.001 ).
A significant “dose-response” relationship was demonstrated with pain severity ( p < 0.001 ).
In individuals with chronic pain, the risk factor composite varied by health behavior, exercise, lower levels and smoking, and higher levels.
Discussion.
The risk factor composite was higher in individuals with chronic pain, greater with increasing pain severity, and influenced by health behaviors.
Conclusions.
Identification of a biological composite sensitive to pain severity and adaptive/maladaptive behaviors would have significant clinical and research utility.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sibille, Kimberly T.& Steingrímsdóttir, Ólöf A.& Fillingim, Roger B.& Stubhaug, Audun& Schirmer, Henrik& Chen, Huaihou…[et al.]. 2016. Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite. Pain Research and Management،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1115498
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sibille, Kimberly T.…[et al.]. Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite. Pain Research and Management No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1115498
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sibille, Kimberly T.& Steingrímsdóttir, Ólöf A.& Fillingim, Roger B.& Stubhaug, Audun& Schirmer, Henrik& Chen, Huaihou…[et al.]. Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite. Pain Research and Management. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1115498
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115498
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر