Decellularized Extracellular Matrix as an In Vitro Model to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation
المؤلفون المشاركون
Tanaka, Masaru
Chen, Guoping
Hoshiba, Takashi
Endo, Chiho
Maruyama, Hiroka
Wakui, Miyuki
Nemoto, Eri
Kawazoe, Naoki
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-06
دولة النشر
مصر
عدد الصفحات
10
الملخص EN
Stem cells are a promising cell source for regenerative medicine.
Stem cell differentiation must be regulated for applications in regenerative medicine.
Stem cells are surrounded by extracellular matrix (ECM) in vivo.
The ECM is composed of many types of proteins and glycosaminoglycans that assemble into a complex structure.
The assembly of ECM molecules influences stem cell differentiation through orchestrated intracellular signaling activated by many ECM molecules.
Therefore, it is important to understand the comprehensive role of the ECM in stem cell differentiation as well as the functions of the individual ECM molecules.
Decellularized ECM is a useful in vitro model for studying the comprehensive roles of ECM because it retains a native-like structure and composition.
Decellularized ECM can be obtained from in vivo tissue ECM or ECM fabricated by cells cultured in vitro.
It is important to select the correct decellularized ECM because each type has different properties.
In this review, tissue-derived and cell-derived decellularized ECMs are compared as in vitro ECM models to examine the comprehensive roles of the ECM in stem cell differentiation.
We also summarize recent studies using decellularized ECM to determine the comprehensive roles of the ECM in stem cell differentiation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hoshiba, Takashi& Chen, Guoping& Endo, Chiho& Maruyama, Hiroka& Wakui, Miyuki& Nemoto, Eri…[et al.]. 2015. Decellularized Extracellular Matrix as an In Vitro Model to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation. Stem Cells International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1116917
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hoshiba, Takashi…[et al.]. Decellularized Extracellular Matrix as an In Vitro Model to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1116917
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hoshiba, Takashi& Chen, Guoping& Endo, Chiho& Maruyama, Hiroka& Wakui, Miyuki& Nemoto, Eri…[et al.]. Decellularized Extracellular Matrix as an In Vitro Model to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation. Stem Cells International. 2015. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1116917
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1116917
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر