Bubaline Cholecyst Derived Extracellular Matrix for Reconstruction of Full Thickness Skin Wounds in Rats
المؤلفون المشاركون
Shakya, Poonam
Sharma, A. K.
Kumar, Naveen
Vellachi, Remya
Mathew, Dayamon D.
Dubey, Prasoon
Shrivastava, Sonal
Shrivastava, Sameer
Maiti, S. K.
Hasan, Anwarul
Singh, K. P.
Singh, Kiranjeet
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-05
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
An acellular cholecyst derived extracellular matrix (b-CEM) of bubaline origin was prepared using anionic biological detergent.
Healing potential of b-CEM was compared with commercially available collagen sheet (b-CS) and open wound (C) in full thickness skin wounds in rats.
Thirty-six clinically healthy adult Sprague Dawley rats of either sex were randomly divided into three equal groups.
Under general anesthesia, a full thickness skin wound (20 × 20 mm2) was created on the dorsum of each rat.
The defect in group I was kept as open wound and was taken as control.
In group II, the defect was repaired with commercially available collagen sheet (b-CS).
In group III, the defect was repaired with cholecyst derived extracellular matrix of bovine origin (b-CEM).
Planimetry, wound contracture, and immunological and histological observations were carried out to evaluate healing process.
Significantly (P<0.05) increased wound contraction was observed in b-CEM (III) as compared to control (I) and b-CS (II) on day 21.
Histologically, improved epithelization, neovascularization, fibroplasia, and best arranged collagen fibers were observed in b-CEM (III) as early as on postimplantation day 21.
These findings indicate that b-CEM have potential for biomedical applications for full thickness skin wound repair in rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shakya, Poonam& Sharma, A. K.& Kumar, Naveen& Vellachi, Remya& Mathew, Dayamon D.& Dubey, Prasoon…[et al.]. 2016. Bubaline Cholecyst Derived Extracellular Matrix for Reconstruction of Full Thickness Skin Wounds in Rats. Scientifica،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1117579
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shakya, Poonam…[et al.]. Bubaline Cholecyst Derived Extracellular Matrix for Reconstruction of Full Thickness Skin Wounds in Rats. Scientifica No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1117579
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shakya, Poonam& Sharma, A. K.& Kumar, Naveen& Vellachi, Remya& Mathew, Dayamon D.& Dubey, Prasoon…[et al.]. Bubaline Cholecyst Derived Extracellular Matrix for Reconstruction of Full Thickness Skin Wounds in Rats. Scientifica. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1117579
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1117579
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر