Quantification of Rifaximin in Tablets by Spectrophotometric Method Ecofriendly in Ultraviolet Region
المؤلفون المشاركون
Salgado, Hérida Regina Nunes
Kogawa, Ana Carolina
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-27
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Rifaximin is an oral nonabsorbable antibiotic that acts locally in the gastrointestinal tract with minimal systemic adverse effects.
It does not have spectrophotometric method ecofriendly in the ultraviolet region described in official compendiums and literature.
The analytical techniques for determination of rifaximin reported in the literature require large amount of time to release results and are significantly onerous.
Furthermore, they use toxic reagents both for the operator and environment and, therefore, cannot be considered environmentally friendly analytical techniques.
The objective of this study was to develop and validate an ecofriendly spectrophotometric method in the ultraviolet region to quantify rifaximin in tablets.
The method was validated, showing linearity, selectivity, precision, accuracy, and robustness.
It was linear over the concentration range of 10–30 mg L−1 with correlation coefficients greater than 0.9999 and limits of detection and quantification of 1.39 and 4.22 mg L−1, respectively.
The validated method is useful and applied for the routine quality control of rifaximin, since it is simple with inexpensive conditions and fast in the release of results, optimizes analysts and equipment, and uses environmentally friendly solvents, being considered a green method, which does not prejudice either the operator or the environment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kogawa, Ana Carolina& Salgado, Hérida Regina Nunes. 2016. Quantification of Rifaximin in Tablets by Spectrophotometric Method Ecofriendly in Ultraviolet Region. Scientifica،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1117621
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kogawa, Ana Carolina& Salgado, Hérida Regina Nunes. Quantification of Rifaximin in Tablets by Spectrophotometric Method Ecofriendly in Ultraviolet Region. Scientifica No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1117621
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kogawa, Ana Carolina& Salgado, Hérida Regina Nunes. Quantification of Rifaximin in Tablets by Spectrophotometric Method Ecofriendly in Ultraviolet Region. Scientifica. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1117621
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1117621
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر