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Increased Blood Pressure Variability Is Associated with Worse Neurologic Outcome in Acute Anterior Circulation Ischemic Stroke
المؤلفون المشاركون
Tirschwell, David
Bennett, Alicia
Stoddard, Gregory J.
Smith, Gordon
Wang, Haimei
Wold, Jana
Chung, Lee
Majersik, Jennifer J.
de Havenon, Adam
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-11-15
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Although research suggests that blood pressure variability (BPV) is detrimental in the weeks to months after acute ischemic stroke, it has not been adequately studied in the acute setting.
Methods.
We reviewed acute ischemic stroke patients from 2007 to 2014 with anterior circulation stroke.
Mean blood pressure and three BPV indices (standard deviation, coefficient of variation, and successive variation) for the intervals 0–24, 0–72, and 0–120 hours after admission were correlated with follow-up modified Rankin Scale (mRS) in ordinal logistic regression models.
The correlation between BPV and mRS was further analyzed by terciles of clinically informative stratifications.
Results.
Two hundred and fifteen patients met inclusion criteria.
At all time intervals, increased systolic BPV was associated with higher mRS, but the relationship was not significant for diastolic BPV or mean blood pressure.
This association was strongest in patients with proximal stroke parent artery vessel occlusion and lower mean blood pressure.
Conclusion.
Increased early systolic BPV is associated with worse neurologic outcome after ischemic stroke.
This association is strongest in patients with lower mean blood pressure and proximal vessel occlusion, often despite endovascular or thrombolytic therapy.
This hypothesis-generating dataset suggests potential benefit for interventions aimed at reducing BPV in this patient population.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
de Havenon, Adam& Bennett, Alicia& Stoddard, Gregory J.& Smith, Gordon& Wang, Haimei& Wold, Jana…[et al.]. 2016. Increased Blood Pressure Variability Is Associated with Worse Neurologic Outcome in Acute Anterior Circulation Ischemic Stroke. Stroke Research and Treatment،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1118494
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
de Havenon, Adam…[et al.]. Increased Blood Pressure Variability Is Associated with Worse Neurologic Outcome in Acute Anterior Circulation Ischemic Stroke. Stroke Research and Treatment No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1118494
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
de Havenon, Adam& Bennett, Alicia& Stoddard, Gregory J.& Smith, Gordon& Wang, Haimei& Wold, Jana…[et al.]. Increased Blood Pressure Variability Is Associated with Worse Neurologic Outcome in Acute Anterior Circulation Ischemic Stroke. Stroke Research and Treatment. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1118494
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1118494
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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