Development and Evaluation of Stability of a Gel Formulation Containing the Monoterpene Borneol
المؤلفون المشاركون
Quintans-Júnior, Lucindo José
Dantas, Milla Gabriela Belarmino
Reis, Silvio Alan Gonçalves Bomfim
Damasceno, Camila Mahara Dias
Rolim, Larissa Araújo
Rolim-Neto, Pedro José
Carvalho, Ferdinando Oliveira
Almeida, Jackson Roberto Guedes da Silva
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-09
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Borneol is a bicyclic monoterpenoid alcohol commonly used in traditional Chinese and Indian medicine.
It is extracted from the essential oil of various medicinal plants.
It has antibacterial, analgesic, and anti-inflammatory action proven in studies that used oral and intraperitoneal applications of this monoterpene in mice.
The current study was designed to develop a topical gel formulation containing the monoterpene borneol using carbopol as gel base and to evaluate its stability.
The prepared formulation was subjected to physical characterization and physical-chemistry assessment.
The gel was prepared from carbopol and 5% of borneol.
The prepared gel was subjected to pharmacotechnical tests such as its pH, viscosity, conductivity, spreadability, centrifugation, and accelerated stability with freezing-thaw cycle.
The borneol was successfully incorporated into the carbopol formulation.
Borneol gel (BG5) showed good stability after eight months of its development and after 12 days in the freeze-thaw cycle, not showing statistical difference in pH value, conductivity, and viscosity before and after test.
Furthermore, the formulation showed a good spreadability.
Therefore, it was concluded that the formulation could be very promising alternative for the topical or transdermal treatment of skin diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dantas, Milla Gabriela Belarmino& Reis, Silvio Alan Gonçalves Bomfim& Damasceno, Camila Mahara Dias& Rolim, Larissa Araújo& Rolim-Neto, Pedro José& Carvalho, Ferdinando Oliveira…[et al.]. 2016. Development and Evaluation of Stability of a Gel Formulation Containing the Monoterpene Borneol. The Scientific World Journal،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1120567
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dantas, Milla Gabriela Belarmino…[et al.]. Development and Evaluation of Stability of a Gel Formulation Containing the Monoterpene Borneol. The Scientific World Journal No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1120567
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dantas, Milla Gabriela Belarmino& Reis, Silvio Alan Gonçalves Bomfim& Damasceno, Camila Mahara Dias& Rolim, Larissa Araújo& Rolim-Neto, Pedro José& Carvalho, Ferdinando Oliveira…[et al.]. Development and Evaluation of Stability of a Gel Formulation Containing the Monoterpene Borneol. The Scientific World Journal. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1120567
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1120567
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر