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Polysaccharide-Based Superporous, Superabsorbent, and Stimuli Responsive Hydrogel from Sweet Basil: A Novel Material for Sustained Drug Release
المؤلفون المشاركون
Lodhi, Bilal Ahmad
Hussain, Muhammad Ajaz
Sher, Muhammad
Haseeb, Muhammad Tahir
Ashraf, Muhammad Umer
Hussain, Syed Zajif
Bukhari, Syed Nasir Abbas
Hussain, Irshad
المصدر
Advances in Polymer Technology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-01
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
This study is carried out on polysaccharide-based hydrogel extracted from the seeds of Ocimum basilicum L.
for its evaluation as a superabsorbent and stimuli responsive biomaterial for sustained release drug delivery system.
O.
basilicum (Syn: Basil) seed hydrogel (BSH) expressed high swelling capacity at pH 6.8 and 7.4 and deionized water.
Highly reversible on-off switching (swelling-deswelling) behavior of BSH was ascertained in deionized water and ethanol, pH 7.4 and 1.2, and deionized water and normal saline.
Scanning electron microscopy (SEM) of BSH has revealed macroporous structure of BSH having average pore size of 1.92 ± 3.83 μm noted after swelling and lyophilization.
BSH containing tablet formulations showed a sustained release pattern of diclofenac sodium (DS) which is dependent on the concentration of BSH.
When comparing with commercially available formulation of DS, even better sustained release behavior of DS was observed in BSH-based formulation.
Super case-II transport mechanism is followed by the DS release from BSH matrix tablet.
Haemocompatibility studies of BSH were also performed and found it nonhaemolytic and nonthrombogenic.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lodhi, Bilal Ahmad& Hussain, Muhammad Ajaz& Sher, Muhammad& Haseeb, Muhammad Tahir& Ashraf, Muhammad Umer& Hussain, Syed Zajif…[et al.]. 2019. Polysaccharide-Based Superporous, Superabsorbent, and Stimuli Responsive Hydrogel from Sweet Basil: A Novel Material for Sustained Drug Release. Advances in Polymer Technology،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1122211
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lodhi, Bilal Ahmad…[et al.]. Polysaccharide-Based Superporous, Superabsorbent, and Stimuli Responsive Hydrogel from Sweet Basil: A Novel Material for Sustained Drug Release. Advances in Polymer Technology No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1122211
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lodhi, Bilal Ahmad& Hussain, Muhammad Ajaz& Sher, Muhammad& Haseeb, Muhammad Tahir& Ashraf, Muhammad Umer& Hussain, Syed Zajif…[et al.]. Polysaccharide-Based Superporous, Superabsorbent, and Stimuli Responsive Hydrogel from Sweet Basil: A Novel Material for Sustained Drug Release. Advances in Polymer Technology. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1122211
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1122211
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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