The Removal of HBV in Plasma by Extracorporeal Immunoadsorption from Plasma: A Potential Therapy of Hepatitis B Patients
المؤلفون المشاركون
Han, Zhenwei
Lu, Xuan
Tang, Yiping
Yang, Yuanyuan
Liu, Qiuchen
Cheng, Pengfei
Zhou, Li
Wang, Yefu
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-23
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To establish a novel HBV specific immunoadsorbent for the removing of HBV particles.
Methods.
The anti-HBsAg monoclonal antibody was immobilized on sepharose beads to produce a sepharose anti-HBs column.
Then the immunoadsorbent was evaluated and characterized by scanning electron microscopy.
In addition, time-dependent effects of the eradication capacity of anti-HBsAg functionalized sepharose beads against HBV were investigated.
Results.
Proposed immunoadsorbents exhibited a favorable biocompatibility as well as specificity.
With the optimized recycle time, the decontamination performance of HBV particles and quantity of HBsAg were assessed either by real-time quantitative PCR or ELISA, which showed that the immunoadsorbent could remove approximately 90% of the HBV and 90% of the HBsAg from human plasma samples.
Conclusions.
All these results indicated that the novel immunoadsorbent could effectively remove HBV particles and likely serve as a novel therapy option or at least supplementary for the treatment regimen of HBV.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Han, Zhenwei& Lu, Xuan& Tang, Yiping& Yang, Yuanyuan& Liu, Qiuchen& Cheng, Pengfei…[et al.]. 2018. The Removal of HBV in Plasma by Extracorporeal Immunoadsorption from Plasma: A Potential Therapy of Hepatitis B Patients. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1124205
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Han, Zhenwei…[et al.]. The Removal of HBV in Plasma by Extracorporeal Immunoadsorption from Plasma: A Potential Therapy of Hepatitis B Patients. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1124205
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Han, Zhenwei& Lu, Xuan& Tang, Yiping& Yang, Yuanyuan& Liu, Qiuchen& Cheng, Pengfei…[et al.]. The Removal of HBV in Plasma by Extracorporeal Immunoadsorption from Plasma: A Potential Therapy of Hepatitis B Patients. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1124205
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1124205
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر